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Drug resistance

  • Selonsertib | ASK1 inhibitor

    CAS:
    1448428-04-3
    Catalog Number:
    10-4696
    Activity:
    ASK1 inhibitor
    Chemical Names:
    5-(4-Cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl)-1,2,4-triazol-3-yl)pyridine-2-yl]benzamide
    Alternate Name:
    GS-4997
    Molecular Weight:
    445.50
    Molecular Formula:
    C24H24FN7O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • SMED-1 | Dexamethasone sensitizer

    Catalog Number:
    10-1606
    Activity:
    Dexamethasone sensitizer
    Chemical Name:
    2-(4-Chlorophenoxy)-2-methyl-N-(2-(piperidin-1-yl)phenyl)propanamide
    Molecular Weight:
    372.89
    Molecular Formula:
    C21H25ClN2O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml), DMF (up to 30 mg/ml), or Ethanol (up to 20 mg/ml)
    Physical Properties:
    Pale grey solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Tepotinib | Selective c-MET inhibitor

    CAS:
    1100598-32-0
    Catalog Number:
    10-5322
    View Product This product has multiple variants. The options may be chosen on the product page

  • Tesmilifene HCl | Anti-estrogen and chemo-potentiating agent

    CAS:
    92981-78-7
    Catalog Number:
    10-1085
    Activity:
    Anti-estrogen and chemo-potentiating agent
    Chemical Names:
    N,N,-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine hydrochloride
    Alternate Names:
    BMS-217380-01; YMB1002; DPPE HCl
    Molecular Weight:
    319.87
    Molecular Formula:
    C19H25NO
    Solubility:
    Soluble in DMSO (30 mg/ml); Water (75 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Verapamil HCl | L-type Ca channel blocker

    CAS:
    152-11-4
    Catalog Number:
    10-1111
    Activity:
    L-type Ca channel blocker
    Chemical Name:
    5-[N-(3,4-Dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochloride
    Molecular Weight:
    491.06
    Molecular Formula:
    C27H38N2O4·HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $27.00
    View Product This product has multiple variants. The options may be chosen on the product page
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