Epigenetics
-
PTC-209 | BMI-1 inhibitor
From $60.00CAS:315704-66-6Catalog Number:10-4022Activity:BMI-1 inhibitorChemical Names:N-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazol[1,2-a]pyrimidin-3-yl)-2-thiazolamineMolecular Weight:495.19Molecular Formula:C17H13Br2N5OSSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Romidepsin | HDAC inhibitor
From $55.00CAS:128517-07-7Catalog Number:10-2365Activity:HDAC inhibitorAlternate Names:FK228, FR901228, DepsipeptideMolecular Weight:540.71Molecular Formula:C24H36N4O6S2Solubility:Soluble in DMSO (up to 10 mg/ml).Physical Properties:Colorless waxy solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
SAHA | HDAC inhibitor
From $35.00CAS:149647-78-9Catalog Number:10-1067Activity:HDAC inhibitorAlternate Names:VorinostatChemical Name:Suberoylanilide-hydroxamic acidMolecular Weight:264.33Molecular Formula:C14H20N2O3Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.Shipping Code:RT -
Salermide | SIRT1 and SIRT2 inhibitor
From $50.00CAS:1105698-15-4Catalog Number:10-1514Activity:Inhibitor of SIRT1 and SIRT2Chemical Name:N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamideMolecular Weight:394.47Molecular Formula:C26H22N2O2Solubility:Soluble in DMSO (up to 40 mg/ml), in DMF (up to 30 mg/ml) or in ethanol (up to 10 mg/ml with warming).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Santacruzamate A | Ultrapotent HDAC2 inhibitor
From $46.00CAS:1477949-42-0Catalog Number:10-3613Activity:Ultrapotent HDAC2 inhibitorChemical Name:N-[4-Oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl esterMolecular Weight:278.35Molecular Formula:C15H22N2O3Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchse as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
