Immuno-oncology Archives | Page 10 of 11

SHP099 | SHP2 inhibitor

CAS:

180747-42-4

Catalog Number:

10-4604

Activity:

SHP2 inhibitor

Chemical Name:

6-(4-Amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine dihydrochloride

Molecular Weight:

425.18

Molecular Formula:

C₁₆H₁₉Cl₂N₅ • 2HCl

Solubility:

Soluble in DMSO (up to 5 mg/ml) or in water (up to at least 20 mg/ml)

Physical Properties:

Yellow solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $75.00
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Sitravatinib | Multikinase inhibitor / Immuno-oncology agent

CAS:

1123837-84-2

Catalog Number:

10-4826

Activity:

Multikinase inhibitor / Immuno-oncology agent

Chemical Name:

1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Alternate Names:

MGCD516

Molecular Weight:

629.68

Molecular Formula:

C₃₃H₂₉N₅O₄S

Solubility:

Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)

Physical Properties:

Off-white solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $50.00
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SR-717 | STING agonist

CAS:

2375421-09-1

Catalog Number:

10-4850

Activity:

STING agonist

Chemical Names:

Lithium 2-(6-(1H-Imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoate

Molecular Weight:

381.27

Molecular Formula:

C₁₅H₈F₂N₅O₃·Li

Solubility:

Soluble in DMSO (>25 mg/ml)

Physical Properties:

Off-white solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month1.

Shipping Code:

RT

From $80.00
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SR0987 |RORγt agonist

CAS:

303126-97-8

Catalog Number:

10-4008

Activity:

RORγt Agonist/Cancer immunotherapy enhancer

Chemical Name:

2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide

Molecular Weight:

397.70

Molecular Formula:

C₁₆H₁₀F₆NO₂

Solubility:

Soluble in DMSO (up to at least 25 mg/ml) and Ethanol (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $65.00
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SX-682 | CXCR1/2 inhibitor

CAS:

1648843-04-2

Catalog Number:

10-4925

Activity:

CXCR1/2 inhibitor

Chemical Names:

[2-[[5-[(4-Fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid

Molecular Weight:

467.20

Molecular Formula:

C₁₉H₁₄BF₄N₃O₄S

Solubility:

Soluble in DMSO (>25 mg/ml)

Physical Properties:

Off-white solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $90.00
Select options

Immuno-oncology

SHP099 | SHP2 inhibitor

Sitravatinib | Multikinase inhibitor / Immuno-oncology agent

SR-717 | STING agonist

SR0987 |RORγt agonist

SX-682 | CXCR1/2 inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Immuno-oncology

SHP099 | SHP2 inhibitor

Sitravatinib | Multikinase inhibitor / Immuno-oncology agent

SR-717 | STING agonist

SR0987 |RORγt agonist

SX-682 | CXCR1/2 inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21