Immuno-oncology Archives | Page 11 of 11

Talabostat mesylate | Pyroptosis inducer / Inflammasome activator

CAS:

150080-09-4

Catalog Number:

10-4005

Activity:

Pyroptosis inducer / Inflammasome activator

Chemical Name:

((2R)-1-((2S)-2-Amino-3-methylbutanoyl)pyrrolidin-2-yl)boronic acid methanesulfonate

Alternate Names:

Val-boroPro; PT-100

Molecular Weight:

310.18

Molecular Formula:

C₉H₁₉BN₂O₃ • CH₃SO₃H

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

97% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $60.00
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Trametinib | MEK inhibitor

CAS:

871700-17-3

Catalog Number:

10-4759

Activity:

MEK inhibitor

Chemical Name:

N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide

Alternate Names:

GSK1120212

Molecular Weight:

615.39

Molecular Formula:

C₂₆H₂₃FIN₅O₄

Solubility:

Soluble in DMSO (up to 20 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $40.00
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URMC-099 | MLK3 inhibitor

CAS:

1229582-33-5

Catalog Number:

10-4012

Activity:

MLK3 inhibitor

Chemical Names:

3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine

Molecular Weight:

421.54

Molecular Formula:

C₂₇H₂₇N₅

Solubility:

Soluble in DMSO (>25 mg/ml)

Physical Properties:

Off-white solid

Purity:

>98% TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $55.00
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WP1066 | JAK2/STAT3 inhibitor

CAS:

857064-38-1

Catalog Number:

10-4831

Activity:

JAK2/STAT3 inhibitor

Chemical Name:

(E)-3-(6-Pyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide

Molecular Weight:

356.22

Molecular Formula:

C₁₈H₁₄BrN₃O

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $79.00
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α-Mangostin | STING agonist (human)

CAS:

6147-11-1

Catalog Number:

10-3433

Activity:

STING agonist (human)

Chemical Name:

1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one

Alternate Names:

Mangostine; Mangostin

Molecular Weight:

410.46

Molecular Formula:

C₂₄H₂₆O₆

Solubility:

Soluble in DMSO (up to 50 mg/ml)

Physical Properties:

Yellow solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $45.00
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Immuno-oncology

Talabostat mesylate | Pyroptosis inducer / Inflammasome activator

Trametinib | MEK inhibitor

URMC-099 | MLK3 inhibitor

WP1066 | JAK2/STAT3 inhibitor

α-Mangostin | STING agonist (human)

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Immuno-oncology

Talabostat mesylate | Pyroptosis inducer / Inflammasome activator

Trametinib | MEK inhibitor

URMC-099 | MLK3 inhibitor

WP1066 | JAK2/STAT3 inhibitor

α-Mangostin | STING agonist (human)

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21