Immuno-oncology Archives | Page 9 of 11

Preladenant | Potent and selective adenosine A2A antagonist

CAS:

377727-87-2

Catalog Number:

10-4102

Chemical Name:

4-(Furan-2-yl)-10-[2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]ethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.0^2,6]dodeca-1(9),2,4,7,11-pentaen-7-amine

Alternate Name:

SCH 420814

Molecular Weight:

503.57

Molecular Formula:

C₂₉H₂₉N₉O₃

Solubility:

Soluble in DMSO (up to 5 mg/ml with warming).

Physical Properties:

Beige solid

Purity:

>98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $70.00
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Prochlorperazine maleate | Endocytosis inhibitor

CAS:

84-02-6

Catalog Number:

10-3474

Activity:

Endocytosis inhibitor

Chemical Name:

2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine dimaleate

Molecular Weight:

606.09

Molecular Formula:

C₂₀H₂₄ClN₃S • 2C₄H₄O₄

Solubility:

Soluble in DMSO (up to 15 mg/ml).

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20° (des.)

Stability:

Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $55.00
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R428 | Potent and selective AXL inhibitor

CAS:

1037624-75-1

Catalog Number:

10-4676

Activity:

Potent and selective AXL inhibitor

Chemical Name:

1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine

Alternate Names:

Bemcentinib; BGB324

Molecular Weight:

506.64

Molecular Formula:

C₃₀H₃₄N₈

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

Yellow solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $75.00
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Rapamycin | mTOR inhibitor

CAS:

53123-88-9

Catalog Number:

10-1104

Activity:

mTOR inhibitor

Alternate Names:

Sirolimus

Molecular Weight:

914.17

Molecular Formula:

C₅₁H₇₉NO₁₃

Solubility:

Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 90 mg/ml).

Physical Properties:

White solid

Purity:

98%
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $52.00
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Resiquimod | TLR7/8 agonist / Immune adjuvant

CAS:

144875-48-9

Catalog Number:

10-2733

Activity:

TLR7/8 agonist / Immune adjuvant

Chemical Name:

1-[4-Amino-2-ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol

Alternate Names:

R848

Molecular Weight:

314.39

Molecular Formula:

C₁₇H₂₂N₄O₂

Solubility:

Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml with warming)

Physical Properties:

White solid

Purity:

>98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $65.00
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Immuno-oncology

Preladenant | Potent and selective adenosine A2A antagonist

Prochlorperazine maleate | Endocytosis inhibitor

R428 | Potent and selective AXL inhibitor

Rapamycin | mTOR inhibitor

Resiquimod | TLR7/8 agonist / Immune adjuvant

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Immuno-oncology

Preladenant | Potent and selective adenosine A2A antagonist

Prochlorperazine maleate | Endocytosis inhibitor

R428 | Potent and selective AXL inhibitor

Rapamycin | mTOR inhibitor

Resiquimod | TLR7/8 agonist / Immune adjuvant

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21