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Immuno-oncology

  • CPI-455 | Lysine demethylase KDM5 inhibitor

    CAS:
    1628208-23-0
    Catalog Number:
    10-4035
    Activity:
    Lysine demethylase KDM5 inhibitor
    Chemical Name:
    7-Oxo-5-phenyl-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
    Molecular Weight:
    278.32
    Molecular Formula:
    C16H14N4O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $90.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Defactinib | Potent FAK inhibitor

    CAS:
    1073154-85-4
    Catalog Number:
    10-4828
    Activity:
    Potent FAK inhibitor
    Chemical Name:
    N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamide
    Molecular Weight:
    510.50
    Molecular Formula:
    C20H21F3N8O3S
    Solubility:
    Soluble in DMSO (up to at least 25mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • DMXAA | STING agonist

    CAS:
    117570-53-3
    Catalog Number:
    10-2676
    Activity:
    STING agonist
    Chemical Name:
    5,6-Dimethylxanthenone-4-acetic acid
    Alternate Names:
    ASA404; Vadimezan
    Molecular Weight:
    282.29
    Molecular Formula:
    C17H14O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in DMF (up to 14 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Dubermatinib Supplier | CAS 1341200-45-0 | Focus Biomolecules

    Dubermatinib | AXL inhibitor

    CAS:
    1341200-45-0
    Catalog Number:
    10-4679
    View Product This product has multiple variants. The options may be chosen on the product page

  • Duvelisib | PI3Kdelta/gamma inhibitor

    CAS:
    1201438-56-3
    Catalog Number:
    10-4788
    Activity:
    PI3Kδ/γ inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one
    Alternative Name:
    IPI-145
    Molecular Weight:
    416.87
    Molecular Formula:
    C22H17ClN6O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
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1-855-FOCUS21

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