Kinases

  • Imatinib mesylate | BCR-ABL inhibitor

    CAS:
    220127-57-1
    Catalog Number:
    10-1060
    Activity:
    BCR-ABL inhibitor
    Alternate Names:
    Gleevec
    Chemical Name:
    4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
    Molecular Weight:
    589.73
    Molecular Formula:
    C29H31N7O CH3SO3H
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Indirubin-3′-monoxime | GSK-3ß and CDK inhibitor

    CAS:
    160807-49-8
    Catalog Number:
    10-1488
    Activity:
    GSK-3β and CDK inhibitor
    Alternate Names:
    Indirubin-3’oxime
    Chemical Name:
    3-[1,3-Dihydro-3-(hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
    Molecular Weight:
    277.29
    Molecular Formula:
    C16H11N3O2
    Solubility:
    Soluble in DMSO (up to 6 mg/ml) or in Ethanol (up to 4 mg/ml).
    Physical Properties:
    Dark red or brown solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Ingenol-3-angelate | PKC activator

    CAS:
    75567-37-2
    Catalog Number:
    10-1244
    Activity:
    PKC activator
    Alternate Names:
    PEP-005
    Molecular Weight:
    460.53
    Molecular Formula:
    C25H34O6
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 4 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $110.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • INK-128 | TORC1/2 inhibitor

    CAS:
    1224844-38-5
    Catalog Number:
    10-3362
    Activity:
    TORC1/2 inhibitor
    Chemical Name:
    3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
    Alternate Names:
    MLN-0128
    Molecular Weight:
    309.33
    Molecular Formula:
    C15H15N7O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC/HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Intelliscreen™ Highly-Selective Kinase Inhibitor Library

    Catalog Number:
    10-7001
    Description:
    166 highly selective inhibitors of various kinases.
    Solubility:
    DMSO
    Supplied As:
    DSMO solution @ 10mM
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $3 700.00
    $3,700.00
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