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Kinases

  • Necrosulfonamide | Necroptosis inhibitor / MLKL inhibitor

    CAS:
    1360614-48-7
    Catalog Number:
    10-4860
    Activity:
    Necroptosis inhibitor / MLKL inhibitor
    Chemical Name:
    (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide
    Molecular Weight:
    461.47
    Molecular Formula:
    C18H15N5O6S2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • NG52 | Phosphoglycerate kinase 1 inhibitor

    CAS:
    212779-48-1
    Catalog Number:
    10-4681
    Activity:
    Phosphoglycerate kinase 1 inhibitor
    Chemical Names:
    2-[[6-(3-Chloroanilino)-9-propan-2-ylpurin-2-yl]amino]ethanol
    Molecular Weight:
    346.82
    Molecular Formula:
    C16H19ClN6O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • NH125 | Eukaryotic elongation factor 2 (eEF-2) kinase inhibitor

    CAS:
    278603-08-0
    Catalog Number:
    10-4840
    Activity:
    Eukaryotic elongation factor 2 (eEF-2) kinase inhibitor
    Chemical Name:
    1-Hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazlium iodide
    Molecular Weight:
    524.56
    Molecular Formula:
    C27H45IN2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Nilotinib | BCR-ABL inhibitor

    CAS:
    641571-10-0
    Catalog Number:
    10-2152
    Activity:
    BCR-ABL inhibitor
    Chemical Name:
    4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
    Alternate Names:
    AMN107
    Molecular Weight:
    529.52
    Molecular Formula:
    C28H22F3N7O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Nintedanib chemical structure Focus Biomolecules

    Nintedanib | VEGFR, PDGFR, and FGFR kinase inhibitor

    CAS:
    656247-17-5
    Catalog Number:
    10-3320
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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