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Kinases

  • LY364947 | ALK5 inhibitor

    CAS:
    396129-53-6
    Catalog Number:
    10-1492
    Activity:
    ALK5 inhibitor
    Alternate Names:
    HTS-466284
    Chemical Name:
    4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinolone
    Molecular Weight:
    272.31
    Molecular Formula:
    C17H12N4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Brown solid
    Purity:
    98% by TLC
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Meleagrin | Met inhibitor, anticancer activity

    CAS:
    71751-77-4
    Catalog Number:
    10-1599
    Activity:
    Met inhibitor, anticancer activity
    Chemical Name:
    (3E,7aR,12aS-7a-(1,1-Dimethyl-2-propen-1-yl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-5-ylmethylene)-12-methoxy-1H,5H-imidazol[1’,2’:1,2]pyrido[2,3-b]indole-2,5(3H)-dione
    Molecular Weight:
    433.46
    Molecular Formula:
    C23H23N5O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $145.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • MK-2206 | Potent and selective AKT inhibitor

    CAS:
    1032350-13-2
    Catalog Number:
    10-4801
    Activity:
    Potent and selective AKT inhibitor
    Chemical Name:
    8-(4-(1-Aminocyclobutyl)phenyl-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one dihydrochloride
    Molecular Weight:
    480.39
    Molecular Formula:
    C25H21N5O • 2HCl
    Solubility:
    Soluble in DMSO (up to 10 mg/ml with warming)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • MTX-531 | Dual EGFR/PI3K inhibitor

    CAS:
    2791417-66-6
    Catalog Number:
    10-4802
    View Product This product has multiple variants. The options may be chosen on the product page

  • Necrosulfonamide | Necroptosis inhibitor / MLKL inhibitor

    CAS:
    1360614-48-7
    Catalog Number:
    10-4860
    Activity:
    Necroptosis inhibitor / MLKL inhibitor
    Chemical Name:
    (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide
    Molecular Weight:
    461.47
    Molecular Formula:
    C18H15N5O6S2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page
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