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Kinases

  • Linsitinib | Inhibits IGF-1R kinase and InsR kinase

    CAS:
    867160-71-2
    Catalog Number:
    10-4814
    Activity:
    Inhibits IGF-1R kinase and InsR kinase
    Chemical Name:
    3-[8-Amino-1-(2-phenyl-7-quinolyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol
    Alternate Names:
    OSI-906
    Molecular Weight:
    421.49
    Molecular Formula:
    C26H23N5O
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • LY2090314 | Wnt/ß-Catenin pathway activator/GSK-3 inhibitor

    CAS:
    603288-22-8
    Catalog Number:
    10-4854
    View Product This product has multiple variants. The options may be chosen on the product page

  • LY2603618 | Potent and selective Chk1 inhibitor

    CAS:
    911222-45-2
    Catalog Number:
    10-4123
    Activity:
    Potent and selective Chk1 inhibitor
    Chemical Name:
    N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N’-(5-methyl-2-pyrazinyl)urea
    Alternate Names:
    Rabusertib
    Molecular Weight:
    436.30
    Molecular Formula:
    C18H22BrN5O3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • LY364947 | ALK5 inhibitor

    CAS:
    396129-53-6
    Catalog Number:
    10-1492
    Activity:
    ALK5 inhibitor
    Alternate Names:
    HTS-466284
    Chemical Name:
    4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinolone
    Molecular Weight:
    272.31
    Molecular Formula:
    C17H12N4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Brown solid
    Purity:
    98% by TLC
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Meleagrin | Met inhibitor, anticancer activity

    CAS:
    71751-77-4
    Catalog Number:
    10-1599
    Activity:
    Met inhibitor, anticancer activity
    Chemical Name:
    (3E,7aR,12aS-7a-(1,1-Dimethyl-2-propen-1-yl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-5-ylmethylene)-12-methoxy-1H,5H-imidazol[1’,2’:1,2]pyrido[2,3-b]indole-2,5(3H)-dione
    Molecular Weight:
    433.46
    Molecular Formula:
    C23H23N5O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $145.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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