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Kinases

  • Pexidartinib | CSF1R inhibitor

    CAS:
    1029044-16-3
    Catalog Number:
    10-4829
    Activity:
    CSF1R inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    5-[(5-Chloro-1H-pyrrolo[2,3.b]pyridine-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
    Alternate Names:
    PLX3397
    Molecular Weight:
    417.81
    Molecular Formula:
    C20H15ClF3N5
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • PF-4708671 dihydrochloride | S6K1 inhibitor

    CAS:
    125517-76-0 (free base)
    Catalog Number:
    10-4856
    Activity:
    S6K1 inhibitor
    Chemical Names:
    2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzimidazole dihydrochloride
    Molecular Weight:
    463.33
    Molecular Formula:
    C19H21F3N6·2HCl
    Solubility:
    Soluble in DMSO (at least 35 mg/ml); Water (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month. Hygroscopic solid – protect from moisture.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • PF-543 supplier | CAS 1706522-79-3 | Focus Biomolecules

    PF-543 HCl | Sphingosine kinase-1 inhibitor

    CAS:
    1706522-79-3
    Catalog Number:
    10-4998
    View Product This product has multiple variants. The options may be chosen on the product page

  • PFK15 | Phosphofructo-2-kinase (PFKFB3) inhibitor

    CAS:
    4382-63-2
    Catalog Number:
    10-4580
    Activity:
    PFKFB3 inhibitor
    Chemical Names:
    1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
    Molecular Weight:
    260.29
    Molecular Formula:
    C17H12N2O
    Solubility:
    Soluble in DMSO (15 mg/ml); ethanol (5 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • PI-103 | Potent inhibitor of PI3-kinase, mTOR, and DNA-PK

    CAS:
    371935-74-9
    Catalog Number:
    10-5406
    Activity:
    Potent inhibitor of PI3-kinase, mTOR and DNA-PK
    Chemical Name:

    3-[4-(4-Morpholinyl)pyrido[3’,2’:4,5]furo[3,2-d]pyrimidin-2-yl]-phenol

    Molecular Weight:
    348.36
    Molecular Formula:
    C19H16N4O3
    Solubility:
    Soluble in DMSO (up to 40 mg/ml)
    Physical Properties:
    White solid
    Purity:

    98% by TLC
    NMR (Conforms)

    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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