Kinases

  • PD 325901 MEK inhibitor

    CAS:
    391210-10-9
    Catalog Number:
    10-2161
    Activity:
    MEK inhibitor
    Chemical Name:
    N-[(2R(-))-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
    Molecular Weight:
    482.2
    Molecular Formula:
    C16H14F3IN2O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • PD-98059 | MEK inhibitor

    CAS:
    167869-21-8
    Catalog Number:
    10-2159
    Activity:
    MEK inhibitor
    Alternate Names:
    2′-Amino-3′-methoxyflavone
    Chemical Name:
    2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
    Molecular Weight:
    267.29
    Molecular Formula:
    C16H13NO3
    Solubility:
    Soluble in DMSO (up to 6 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • PD173074 | FGFR inhibitor

    CAS:
    219580-11-7
    Catalog Number:
    10-4505
    Activity:
    FGFR inhibitor
    Chemical Name:
    1-t-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)-pyrido[2,3-d]pyrimidin-7-yl)urea
    Molecular Weight:
    523.67
    Molecular Formula:
    C28H41N7O3
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    Yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $35.00
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  • Pexidartinib | CSF1R inhibitor

    CAS:
    1029044-16-3
    Catalog Number:
    10-4829
    Activity:
    CSF1R inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    5-[(5-Chloro-1H-pyrrolo[2,3.b]pyridine-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
    Alternate Names:
    PLX3397
    Molecular Weight:
    417.81
    Molecular Formula:
    C20H15ClF3N5
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
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  • PF-4708671 dihydrochloride | S6K1 inhibitor

    CAS:
    125517-76-0 (free base)
    Catalog Number:
    10-4856
    Activity:
    S6K1 inhibitor
    Chemical Names:
    2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzimidazole dihydrochloride
    Molecular Weight:
    463.33
    Molecular Formula:
    C19H21F3N6·2HCl
    Solubility:
    Soluble in DMSO (at least 35 mg/ml); Water (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month. Hygroscopic solid – protect from moisture.
    Shipping Code:
    RT
    From $40.00
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