Kinases Archives

PLX4032 | BRAF inhibitor

CAS:

918504-65-1

Catalog Number:

10-2928

Activity:

BRAF inhibitor

Chemical Name:

N-[3-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide

Alternate Names:

Vemurafenib, R7204, Ro 51-85426

Molecular Weight:

489.92

Molecular Formula:

C₂₃H₁₈ClF₂N₃O₃S

Solubility:

Soluble in DMSO (up to 100 mg/ml)

Physical Properties:

White or off-white solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $40.00
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PLX4720 | Mutant B-Raf inhibitor

CAS:

918505-84-7

Catalog Number:

10-5113

Activity:

Mutant B-Raf inhibitor

Chemical Names:

N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide

Molecular Weight:

413.82

Molecular Formula:

C₁₇H₁₄ClF₂N₃O₃S

Solubility:

Soluble in DMSO (30 mg/ml with warming)

Physical Properties:

White solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $55.00
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Ponatinib | Bcr-Abl and multikinase inhibitor

CAS:

943319-70-8

Catalog Number:

10-5064

Activity:

Bcr-Abl and multikinase inhibitor

Chemical Name:

3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide

Alternate Name:

AP-24534

Molecular Weight:

532.56

Molecular Formula:

C₂₉H₂₇F3₂N₆O

Solubility:

Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml with warming).

Physical Properties:

Yellow solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $50.00
View Product This product has multiple variants. The options may be chosen on the product page
PP1 | Src family kinase inhibitor

CAS:

172889-26-8

Catalog Number:

10-1184

Activity:

Src family kinase inhibitor

Chemical Name:

4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine

Molecular Weight:

281.63

Molecular Formula:

C₁₆H₁₉N₅

Solubility:

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).

Physical Properties:

White or off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $65.00
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PP2 | Src family kinase inhibitor

CAS:

172889-27-9

Catalog Number:

10-1407

Activity:

Src family kinase inhibitor

Chemical Name:

3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Molecular Weight:

301.78

Molecular Formula:

C₁₅H₁₆ClN₅

Solubility:

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 3 mg/ml with warming).

Physical Properties:

Off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $60.00
View Product This product has multiple variants. The options may be chosen on the product page

Kinases

PLX4032 | BRAF inhibitor

PLX4720 | Mutant B-Raf inhibitor

Ponatinib | Bcr-Abl and multikinase inhibitor

PP1 | Src family kinase inhibitor

PP2 | Src family kinase inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

PLX4032 | BRAF inhibitor

PLX4720 | Mutant B-Raf inhibitor

Ponatinib | Bcr-Abl and multikinase inhibitor

PP1 | Src family kinase inhibitor

PP2 | Src family kinase inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21