Kinases Archives

Trametinib | MEK inhibitor

CAS:

871700-17-3

Catalog Number:

10-4759

Activity:

MEK inhibitor

Chemical Name:

N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide

Alternate Names:

GSK1120212

Molecular Weight:

615.39

Molecular Formula:

C₂₆H₂₃FIN₅O₄

Solubility:

Soluble in DMSO (up to 20 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $40.00
View Product This product has multiple variants. The options may be chosen on the product page
U0126 | Selective MEK1 and MEK2 inhibitor

CAS:

109511-58-2

Catalog Number:

10-2179

Activity:

Selective MEK1 and MEK2 inhibitor

Chemical Name:

1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene

Molecular Weight:

380.49

Molecular Formula:

C₁₈H₁₆N₆S₂

Solubility:

Soluble in DMSO (up to 200 mg/ml).

Physical Properties:

White solid

Purity:

99% by HPLC

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $90.00
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Vandetanib | VEGFR2 inhibitor

CAS:

443913-73-3

Catalog Number:

10-2185

Activity:

VEGFR2 inhibitor

Chemical Names:

4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-yl)methoxy]quinazoline

Alternate Name:

ZD6474

Molecular Weight:

475.35

Molecular Formula:

C₂₂H₂₄BrFN₄O₂

Solubility:

Soluble in DMSO (30 mg/ml); Ethanol (10 mg/ml with warming)

Physical Properties:

White to off-white solid

Purity:

98% TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $50.00
View Product This product has multiple variants. The options may be chosen on the product page
Vatalanib 2HCl | VEGFR kinase inhibitor

CAS:

212141-51-0

Catalog Number:

10-2183

Activity:

VEGFRK inhibitor

Chemical Name:

N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochloride

Alternate Names:

CGP-79787; PTK-787; ZK222584

Molecular Weight:

419.73

Molecular Formula:

C₂₀H₁₅ClN₄·2HCl

Solubility:

Soluble in DMSO (up to 20 mg/ml with warming) or in Water (up to 100 mg/ml)

Physical Properties:

White or off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $50.00
View Product This product has multiple variants. The options may be chosen on the product page
VE-821 | Potent and selective ATR inhibitor

CAS:

1232410-49-9

Catalog Number:

10-5589

Activity:

ATR inhibitor

Chemical Names:

3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide

Molecular Weight:

368.41

Molecular Formula:

C₁₈H₁₆N₄O₃S

Solubility:

Soluble in DMSO (40 mg/ml)

Physical Properties:

Beige solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $80.00
View Product This product has multiple variants. The options may be chosen on the product page

Kinases

Trametinib | MEK inhibitor

U0126 | Selective MEK1 and MEK2 inhibitor

Vandetanib | VEGFR2 inhibitor

Vatalanib 2HCl | VEGFR kinase inhibitor

VE-821 | Potent and selective ATR inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

Trametinib | MEK inhibitor

U0126 | Selective MEK1 and MEK2 inhibitor

Vandetanib | VEGFR2 inhibitor

Vatalanib 2HCl | VEGFR kinase inhibitor

VE-821 | Potent and selective ATR inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21