• EX-527 | SIRT1 inhibitor

    CAS:
    49843-98-3
    Catalog Number:
    10-1083
    Activity:
    SIRT1 inhibitor
    Chemical Name:
    6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
    Molecular Weight:
    248.71
    Molecular Formula:
    C13H13ClN2O
    Solubility:
    Soluble in DMSO (up to 18 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    Light yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Leptomycin B | Nuclear export inhibitor

    CAS:
    87081-35-4
    Catalog Number:
    10-2084
    Activity:
    Nuclear export inhibitor
    Molecular Weight:
    540.75
    Molecular Formula:
    C33H48O6
    Solubility:
    Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.
    Physical Properties:
    Solution in ethanol (1mg/ml)
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions or dilutions in DMSO are not stable. Solutions should be made fresh and used within one working day.
    Shipping Code:
    RT
    From $60.00
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  • NSC59984 | p53 activator

    CAS:
    803647-40-7
    Catalog Number:
    10-3148
    Activity:
    P53 activator
    Chemical Name:
    (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one
    Molecular Weight:
    265.27
    Molecular Formula:
    C12H15N3O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • NSC66811 | p53/mdm2 inhibitor

    CAS:
    6964-62-1
    Catalog Number:
    10-1334
    Activity:
    p53/mdm2 inhibitor
    Chemical Name:
    2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol
    Molecular Weight:
    340.43
    Molecular Formula:
    C23H20N2O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    97% by TLC/HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $100.00
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  • Nutlin-3 | p53/mdm2 inhibitor

    CAS:
    548472-68-0
    Catalog Number:
    10-1350
    Activity:
    p53/mdm2 inhibitor
    Chemical Name:
    (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
    Molecular Weight:
    581.51
    Molecular Formula:
    C30H30Cl2N4O4
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $100.00
    View Product This product has multiple variants. The options may be chosen on the product page
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