Cancer immunotherapy
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Acalabrutinib | Highly selective BTK inhibitor
From $45.00CAS:1420477-60-6Catalog Number:10-4806Alternate Name:ACP-196Activity:Highly selective BTK inhibitorChemical Name:4-[8-Amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamideMolecular Weight:465.52Molecular Formula:C26H23N7O2Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
BMS-202 | PD-1/PD-L1 inhibitor
From $85.00CAS:1675203-84-5Catalog Number:10-4900Activity:PD-1/PD-L1 inhibitorChemical Name:N-[2-[[2-Methoxy-6-[(2-methyl-3-phenylphenyl)methoxy]pyridine-3-yl]methylamino]ethyl]acetamideAlternate Name:PD-1/PD-L1 Inhibitor 2Molecular Weight:419.53Molecular Formula:C25H29N3O3Solubility:Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
BX795 | Dual TBK1/IKKε inhibitor – enhances lentiviral transduction efficiency
From $65.00CAS:702675-74-9Catalog Number:10-4677Activity:Dual inhibitor of TBK1/IKKεChemical Names:N-[3-[[5-Iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamideMolecular Weight:591.47Molecular Formula:C23H26IN7O2SSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white solidPurity:>97% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
CBL0137 | Inhibitor of the histone chaperone FACT
CAS:1197996-80-7Catalog Number:10-4026 -
CPI-444 | Adenosine A2A receptor antagonist
From $95.00CAS:1202402-40-1Catalog Number:10-4101Activity:Adenosine A2A receptor antagonistChemical Name:7-(5-Methylfuran-2-yl)-3-[[6-[[(3S)-oxolan-3-yl]oxymethyl]pyridine-2-yl]triazolo[4,5-d]pyrimidin-5-amineAlternate Name:CiforadenantMolecular Weight:407.43Molecular Formula:C20H21N7O3Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Beige solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
