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Cancer immunotherapy

  • Acalabrutinib | Highly selective BTK inhibitor

    CAS:
    1420477-60-6
    Catalog Number:
    10-4806
    Alternate Name:
    ACP-196
    Activity:
    Highly selective BTK inhibitor
    Chemical Name:
    4-[8-Amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
    Molecular Weight:
    465.52
    Molecular Formula:
    C26H23N7O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)

     

    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • BMS-202 | PD-1/PD-L1 inhibitor

    CAS:
    1675203-84-5
    Catalog Number:
    10-4900
    Activity:
    PD-1/PD-L1 inhibitor
    Chemical Name:
    N-[2-[[2-Methoxy-6-[(2-methyl-3-phenylphenyl)methoxy]pyridine-3-yl]methylamino]ethyl]acetamide
    Alternate Name:
    PD-1/PD-L1 Inhibitor 2
    Molecular Weight:
    419.53
    Molecular Formula:
    C25H29N3O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $85.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • BX795 | Dual TBK1/IKKε inhibitor – enhances lentiviral transduction efficiency

    CAS:
    702675-74-9
    Catalog Number:
    10-4677
    Activity:
    Dual inhibitor of TBK1/IKKε
    Chemical Names:
    N-[3-[[5-Iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
    Molecular Weight:
    591.47
    Molecular Formula:
    C23H26IN7O2S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >97% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • CBL0137 supplier | CAS 1197996-80-7 | Focus Biomolecules

    CBL0137 | Inhibitor of the histone chaperone FACT

    CAS:
    1197996-80-7
    Catalog Number:
    10-4026
    View Product This product has multiple variants. The options may be chosen on the product page

  • CPI-444 | Adenosine A2A receptor antagonist

    CAS:
    1202402-40-1
    Catalog Number:
    10-4101
    Activity:
    Adenosine A2A receptor antagonist
    Chemical Name:
    7-(5-Methylfuran-2-yl)-3-[[6-[[(3S)-oxolan-3-yl]oxymethyl]pyridine-2-yl]triazolo[4,5-d]pyrimidin-5-amine
    Alternate Name:
    Ciforadenant
    Molecular Weight:
    407.43
    Molecular Formula:
    C20H21N7O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $95.00
    View Product This product has multiple variants. The options may be chosen on the product page
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