Natural products

‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).

  • Cycloheximide | Protein synthesis inhibitor

    CAS:
    66-81-9
    Catalog Number:
    10-1117
    Activity:
    Protein synthesis inhibitor
    Alternate Names:
    U-4527
    Chemical Name:
    4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
    Molecular Weight:
    281.35
    Molecular Formula:
    C15H23NO4
    Solubility:
    Soluble in Ethanol (up to 14 mg/ml) or in Water (up to 7 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    96% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in ethanol or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Cyclopamine | Inhibits hedgehog signaling

    CAS:
    4449-51-8
    Catalog Number:
    10-1082
    Activity:
    Inhibits hedgehog signaling
    Molecular Weight:
    411.63
    Molecular Formula:
    C27H41NO2
    Solubility:
    Soluble in DMSO (up to 4 mg/ml) or in Ethanol (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $56.00
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  • Cyclosporin A | Inhibits mitochondrial permeability pore opening

    CAS:
    59865-13-3
    Catalog Number:
    10-1119
    Activity:
    Inhibits mitochondrial permeability pore opening
    Molecular Weight:
    1202.65
    Molecular Formula:
    C62H111N11O12
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Cytochalasin B | Actin filament disrupting agent

    CAS:
    14930-96-2
    Catalog Number:
    10-2069
    Activity:
    Actin filament disrupting agent
    Fermentation product:
    from Drechslera dematioidea
    Alternate Name:
    NSC107658; Phominone
    Molecular Weight:
    479.61
    Molecular Formula:
    C29H37NO5
    Solubility:
    Soluble in DMSO (up to 5 mg/ml); Ethanol (10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • Cytochalasin D | Disrupts actin filaments

    CAS:
    22144-77-0
    Catalog Number:
    10-2071
    Activity:
    Disrupts actin filaments
    Chemical Name:
    (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione
    Molecular Weight:
    507.63
    Molecular Formula:
    C30H37NO6
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $68.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Damnacanthal | p56 Lck inhibitor

    CAS:
    477-84-9
    Catalog Number:
    10-2516
    Activity:
    p56 Lck inhibitor
    Chemical Name:
    9,10-Dihydroxy-3-hydroxy-1-methoxy-9,10-dioxo-2-anthracenecarboxaldehyde
    Molecular Weight:
    282.25
    Molecular Formula:
    C16H10O5
    Solubility:
    Soluble in DMSO (up to 7 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $130.00
    View Product This product has multiple variants. The options may be chosen on the product page
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