Natural products

‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).

  • Bongkrekic Acid | Inhibits MPT pore opening

    CAS:
    11076-19-0
    Catalog Number:
    10-2751
    Activity:
    Inhibits MPT pore opening
    Chemical Name:
    3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic acid
    Molecular Weight:
    486.61
    Molecular Formula:
    C28H38O7
    Solubility:
    Miscible with DMSO.
    Physical Properties:
    Solution at 1 mg/mL (2 mM) in 0.01M Tris buffer pH 7.5 (contains 1 mg net bongkrekic acid per mL)
    Purity:
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    Blue Ice
    From $160.00
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  • Borrelidin | Angiogenesis inhibitor

    CAS:
    7184-60-3
    Catalog Number:
    10-1399
    Activity:
    Angiogenesis inhibitor
    Alternate Names:
    U-78548; C2989; Treponemycin
    Chemical Name:
    Fermentation from Streptomyces sp.
    Molecular Weight:
    489.66
    Molecular Formula:
    C28H43NO6
    Solubility:
    Soluble in DMSO or in Ethanol.
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $190.00
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  • brefeldin a chemical structure

    Brefeldin A | Inhibits intracellular transport

    CAS:
    20350-15-6
    Catalog Number:
    10-1071
    Activity:
    Inhibits intracellular transport
    Alternate Names:
    Fermentation product from Penicillium brefeldianum
    Molecular Weight:
    280.37
    Molecular Formula:
    C16H24O4
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
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  • Caerulomycin A | Blocks STAT1 signaling / Immunosuppressant

    CAS:
    21802-37-9
    Catalog Number:
    10-2897
    Activity:
    Blocks STAT1 signaling / Immunosuppressant
    Chemical Name:
    (2Z)-4-Methoxy-2-(nitrosomethylidene)-6-pyridin-2-yl-1H-pyridine
    Molecular Weight:
    229.23
    Molecular Formula:
    C12H11N3O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $80.00
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  • Cafestol chemical structure Focus Biomolecules

    Cafestol | Neuroprotective

    CAS:
    469-83-0
    Catalog Number:
    10-2251
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  • Camptothecin | Topoisomerase I inhibitor

    CAS:
    7689-03-4
    Catalog Number:
    10-1041
    Activity:
    Topoisomerase I inhibitor
    Chemical Name:
    (S)-4-Ethyl-4-hydroxy-1H-pyrano-[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
    Molecular Weight:
    348.35
    Molecular Formula:
    C20H16N2O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98%
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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