ALK

  • Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic

    CAS:
    700874-72-2
    Catalog Number:
    10-4110
    Activity:
    Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeutic
    Chemical Name:
    4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
    Alternate Names:
    LY2157299
    Molecular Weight:
    369.43
    Molecular Formula:
    C22H19N5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • GW788388 | TGF-ß receptor kinase inhibitor

    CAS:
    452342-67-5
    Catalog Number:
    10-5521
    Activity:
    TGF-ß receptor kinase inhibitor
    Chemical Names:
    4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide
    Molecular Weight:
    425.49
    Molecular Formula:
    C25H23N5O2
    Solubility:
    Soluble in DMSO (18 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • LDN-193189 | Inhibitor of ALK2 and ALK3

    CAS:
    1435934-00-1
    Catalog Number:
    10-4764
    Activity:
    Inhibitor of ALK2 and ALK3
    Chemical Name:
    4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline dihydrochloride
    Molecular Weight:
    479.40
    Molecular Formula:
    C25H22N6·2HCl
    Solubility:
    Soluble in DMSO or in Water (up to 5 mg/ml)
    Physical Properties:
    Orange-yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • LY364947 | ALK5 inhibitor

    CAS:
    396129-53-6
    Catalog Number:
    10-1492
    Activity:
    ALK5 inhibitor
    Alternate Names:
    HTS-466284
    Chemical Name:
    4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinolone
    Molecular Weight:
    272.31
    Molecular Formula:
    C17H12N4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Brown solid
    Purity:
    98% by TLC
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • MU1700 | Selective ALK1/2 inhibitor

    CAS:
    1360905-04-9 (free base)
    Catalog Number:
    10-4746
    View Product This product has multiple variants. The options may be chosen on the product page
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