Cell Cycle / Cell Division

  • SNS-314 mesylate | Aurora kinase inhibitor

    CAS:
    1146618-41-8
    Catalog Number:
    10-4779
    Activity:
    Aurora kinase inhibitor
    Chemical Name:
    1-(3-Chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea mesylate
    Molecular Weight:
    527.04
    Molecular Formula:
    C18H15ClN6OS2 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $70.00
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  • SU9516 | pan-specific CDK inhibitor

    CAS:
    SU9516
    Catalog Number:
    10-5705
    Activity:
    pan-specific CDK inhibitor
    Chemical Names:
    (Z)-1,3-Dihydro-3-(1H-imidazol-4-ylmethylene)-5-methoxy-2H-2-one
    Molecular Weight:
    241.25
    Molecular Formula:
    C13H11N3O2
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $75.00
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  • THZ1 | Potent and selective CDK7 inhibitor

    CAS:
    1604810-83-4
    Catalog Number:
    10-4120
    Activity:
    Potent and selective CDK7 inhibitor
    Chemical Name:
    (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide
    Molecular Weight:
    566.05
    Molecular Formula:
    C31H28ClN7O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
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  • Volasertib | Potent and selective inhibitor of Polo-like kinase 1

    CAS:
    755038-65-4
    Catalog Number:
    10-4818
    Activity:
    Potent and selective inhibitor of Polo-like kinase 1
    Chemical Name:
    N-[4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-4-[[(7R)-7-ethyl-5-methyl-6-oxo-8-propan-2-yl-7H-pteridin-2-yl]amino]-3-methoxybenzamide
    Alternate Name:
    BI 6727
    Molecular Weight:
    618.82
    Molecular Formula:
    C34H50N8O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • XL413·HCl | Cdc7 inhibitor/CRISPR enhancer

    CAS:
    2062200-97-7
    Catalog Number:
    10-4414
    View Product This product has multiple variants. The options may be chosen on the product page
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