Cell Cycle / Cell Division

  • THZ1 | Potent and selective CDK7 inhibitor

    CAS:
    1604810-83-4
    Catalog Number:
    10-4120
    Activity:
    Potent and selective CDK7 inhibitor
    Chemical Name:
    (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide
    Molecular Weight:
    566.05
    Molecular Formula:
    C31H28ClN7O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Volasertib | Potent and selective inhibitor of Polo-like kinase 1

    CAS:
    755038-65-4
    Catalog Number:
    10-4818
    Activity:
    Potent and selective inhibitor of Polo-like kinase 1
    Chemical Name:
    N-[4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-4-[[(7R)-7-ethyl-5-methyl-6-oxo-8-propan-2-yl-7H-pteridin-2-yl]amino]-3-methoxybenzamide
    Alternate Name:
    BI 6727
    Molecular Weight:
    618.82
    Molecular Formula:
    C34H50N8O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • XL413·HCl | Cdc7 inhibitor/CRISPR enhancer

    CAS:
    2062200-97-7
    Catalog Number:
    10-4414
    View Product This product has multiple variants. The options may be chosen on the product page
  • ZM-447439 | Aurora B kinase inhibitor

    CAS:
    331771-20-1
    Catalog Number:
    10-1037
    Activity:
    Aurora B kinase inhibitor
    Chemical Name:
    N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
    Molecular Weight:
    513.59
    Molecular Formula:
    C29H31N5O4
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase  as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $52.00
    View Product This product has multiple variants. The options may be chosen on the product page
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