Highly Selective Inhibitors
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TH257 | Allosteric LIM kinase inhibitor
From $60.00CAS:2244678-29-1Catalog Number:10-4418Activity:Allosteric LIM kinase inhibitorChemical Names:N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamideMolecular Weight:422.54Molecular Formula:C24H26N2O3SSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White to off-white glassy solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Tofacitinib | JAK inhibitor
From $60.00CAS:477600-75-2Catalog Number:10-2177Activity:JAK inhibitorAlternate Names:Tasocitinib, CP-690550Molecular Weight:312.37Molecular Formula:C16H20N6OSolubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).Physical Properties:Off-white solidPurity:99% by HPLC and TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Trametinib | MEK inhibitor
From $40.00CAS:871700-17-3Catalog Number:10-4759Activity:MEK inhibitorChemical Name:N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamideAlternate Names:GSK1120212Molecular Weight:615.39Molecular Formula:C26H23FIN5O4Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Vatalanib 2HCl | VEGFR kinase inhibitor
From $50.00CAS:212141-51-0Catalog Number:10-2183Activity:VEGFRK inhibitorChemical Name:N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochlorideAlternate Names:CGP-79787; PTK-787; ZK222584Molecular Weight:419.73Molecular Formula:C20H15ClN4·2HClSolubility:Soluble in DMSO (up to 20 mg/ml with warming) or in Water (up to 100 mg/ml)Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT
