JAK

  • AG-490 | JAK2 inhibitor

    CAS:
    133550-30-8
    Catalog Number:
    10-1091
    Activity:
    JAK2 inhibitor
    Chemical Name:
    (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide
    Molecular Weight:
    294.31
    Molecular Formula:
    C17H14N2O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml), in DMF (up to 40 mg/ml), or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Baricitinib | JAK 1/2 inhibitor

    CAS:
    1187594-09-7
    Catalog Number:
    10-3893
    Activity:
    JAK 1/2 inhibitor
    Chemical Name:
    1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidine-acetonitrile
    Alternate Name:
    INCB028050; LY3009104
    Molecular Weight:
    371.42
    Molecular Formula:
    C16H17N7O2S
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 50 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $48.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Filgotinib | JAK1 inhibitor

    CAS:
    1206161-97-8
    Catalog Number:
    10-5145
    Activity:
    JAK1 inhibitor
    Chemical Names:
    N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-ɑ]pyridin-2-yl]-cyclopropanecarboxamide
    GLPG0634; GS-6034
    Molecular Weight:
    425.50
    Molecular Formula:
    C21H23N5O3S
    Solubility:
    Soluble in DMSO (15 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $65.00
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  • NSC33994 | JAK2 inhibitor

    CAS:
    82058-16-0
    Catalog Number:
    10-1530
    Activity:
    JAK2 inhibitor
    Alternate Names:
    G6
    Chemical Name:
    E-4,4′-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol
    Molecular Weight:
    436.65
    Molecular Formula:
    C28H42N2O2
    Solubility:
    Soluble in DMSO (up to 2 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $85.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Pyridone 6 | pan-JAK inhibitor

    CAS:
    457081-03-7
    Catalog Number:
    10-5555
    Activity:
    pan-JAK inhibitor
    Chemical Names:
    2-(tert-Butyl)-9-fluoro-1Hbenzo[h]imidazo[4,5-f]isoquinolin-7(6H)-one; JAK Inhibitor I
    Molecular Weight:
    309.34
    Molecular Formula:
    C18H16FN3O
    Solubility:
    Soluble in DMSO (30 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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