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Cellular Stress

  • NVP-BEZ235 | PI3-K and mTOR inhibitor

    CAS:
    915019-65-7
    Catalog Number:
    10-2153
    Activity:
    PI 3-K and mTOR inhibitor
    Chemical Name:
    2-Methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
    Molecular Weight:
    469.55
    Molecular Formula:
    C30H23N5O
    Solubility:
    Soluble in DMSO (up to 1 mg/ml with warming) or in DMF (up to 10 mg/ml, dissolves slowly, requires heating to 75¡C).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Ophiobolin A | Autophagy inducer / Anticancer

    CAS:
    4611-05-6
    Catalog Number:
    10-3150
    Activity:
    Autophagy inducer / Anticancer
    Alternate Names:
    Cochliobolin A; Ophiobalin; NSC 114340
    Molecular Weight:
    400.55
    Molecular Formula:
    C25H36O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Piperlongumine | Glutathione sponge / Increases ROS levels

    CAS:
    20069-09-4
    Catalog Number:
    10-2377
    Activity:
    Glutathione sponge / Increases ROS levels
    Chemical Name:
    (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one
    Molecular Weight:
    317.34
    Molecular Formula:
    C17H19NO5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Cream-colored solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • PRIMA-1(MET) | Reactivates mutant p53

    CAS:
    5291-32-7
    Catalog Number:
    10-4175
    Activity:
    Reactivates mutant p53
    Chemical Name:
    2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
    Alternate Names:
    APR-246
    Molecular Weight:
    199.25
    Molecular Formula:
    C10H17NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    95%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Quinacrine HCl | Antiprotozoan / Anticancer

    CAS:
    69-05-6
    Catalog Number:
    10-4251
    Activity:
    Antiprotozoan / Anticancer
    Chemical Name:
    6-Chloro-9-(4-diethylamino-1-methylbutyl)amino-2-methoxyacridine dihydrochloride
    Molecular Weight:
    472.88
    Molecular Formula:
    C23H30ClN3O • 2HCl
    Solubility:
    Soluble in Water (up to at least 25 mg/ml) or in DMSO (up to at least 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Solutions in water should be made fresh daily.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
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