Chemotherapeutics

  • Mitomycin C | DNA crosslinking and damaging agent

    CAS:
    50-07-7
    Catalog Number:
    10-1170
    Activity:
    DNA crosslinking and damaging agent
    Chemical Name:
    Natural fermentation product from Streptomyces sp.
    Molecular Weight:
    334.33
    Molecular Formula:
    C15H18N4O5
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).
    Physical Properties:
    Blue-violet solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.
    Shipping Code:
    RT
    From $55.00
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  • MRTX849 | Covalent KRASG12C Inhibitor

    CAS:
    2326521-71-3
    Catalog Number:
    10-4985
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  • Nilotinib | BCR-ABL inhibitor

    CAS:
    641571-10-0
    Catalog Number:
    10-2152
    Activity:
    BCR-ABL inhibitor
    Chemical Name:
    4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
    Alternate Names:
    AMN107
    Molecular Weight:
    529.52
    Molecular Formula:
    C28H22F3N7O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
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  • Olaparib | PARP1 inhibitor

    CAS:
    763113-22-0
    Catalog Number:
    10-2154
    Activity:
    PARP1 inhibitor
    Chemical Name:
    4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-one
    Alternate Names:
    AZD-2281; KU-59436
    Molecular Weight:
    434.47
    Molecular Formula:
    C24H23FN4O3
    Solubility:
    Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • Pemetrexed 2Na | Multitargeted antifolate

    CAS:
    357166-29-1
    Catalog Number:
    10-2162
    Activity:
    Multi-targeted antifolate
    Chemical Name:
    N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, disodium salt
    Molecular Weight:
    597.49
    Molecular Formula:
    C20H19N5O6 • 2Na • 7H2O
    Solubility:
    Soluble in Water (up to 100 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC and HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 31month.
    Shipping Code:
    RT
    From $70.00
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