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Immuno-oncology

  • SR-717 | STING agonist

    CAS:
    2375421-09-1
    Catalog Number:
    10-4850
    Activity:
    STING agonist
    Chemical Names:
    Lithium 2-(6-(1H-Imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoate
    Molecular Weight:
    381.27
    Molecular Formula:
    C15H8F2N5O3·Li
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month1.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • SR0987 |RORγt agonist

    CAS:
    303126-97-8
    Catalog Number:
    10-4008
    Activity:
    RORγt Agonist/Cancer immunotherapy enhancer
    Chemical Name:
    2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide
    Molecular Weight:
    397.70
    Molecular Formula:
    C16H10F6NO2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) and Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • SX-682 | CXCR1/2 inhibitor

    CAS:
    1648843-04-2
    Catalog Number:
    10-4925
    Activity:
    CXCR1/2 inhibitor
    Chemical Names:
    [2-[[5-[(4-Fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid
    Molecular Weight:
    467.20
    Molecular Formula:
    C19H14BF4N3O4S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $90.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Talabostat mesylate | Pyroptosis inducer / Inflammasome activator

    CAS:
    150080-09-4
    Catalog Number:
    10-4005
    Activity:
    Pyroptosis inducer / Inflammasome activator
    Chemical Name:
    ((2R)-1-((2S)-2-Amino-3-methylbutanoyl)pyrrolidin-2-yl)boronic acid methanesulfonate
    Alternate Names:
    Val-boroPro; PT-100
    Molecular Weight:
    310.18
    Molecular Formula:
    C9H19BN2O3 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Trametinib | MEK inhibitor

    CAS:
    871700-17-3
    Catalog Number:
    10-4759
    Activity:
    MEK inhibitor
    Chemical Name:
    N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide
    Alternate Names:
    GSK1120212
    Molecular Weight:
    615.39
    Molecular Formula:
    C26H23FIN5O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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