Immuno-oncology
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SHP099 | SHP2 inhibitor
From $75.00CAS:1801747-11-4Catalog Number:10-4604Activity:SHP2 inhibitorChemical Name:6-(4-Amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine dihydrochlorideMolecular Weight:425.18Molecular Formula:C16H19Cl2N5 • 2HClSolubility:Soluble in DMSO (up to 5 mg/ml) or in water (up to at least 20 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Sitravatinib | Multikinase inhibitor / Immuno-oncology agent
From $50.00CAS:1123837-84-2Catalog Number:10-4826Activity:Multikinase inhibitor / Immuno-oncology agentChemical Name:1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideAlternate Names:MGCD516Molecular Weight:629.68Molecular Formula:C33H29N5O4SSolubility:Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
SR-717 | STING agonist
From $80.00CAS:2375421-09-1Catalog Number:10-4850Activity:STING agonistChemical Names:Lithium 2-(6-(1H-Imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoateMolecular Weight:381.27Molecular Formula:C15H8F2N5O3·LiSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month1.Shipping Code:RT -
SR0987 |RORγt agonist
From $65.00CAS:303126-97-8Catalog Number:10-4008Activity:RORγt Agonist/Cancer immunotherapy enhancerChemical Name:2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamideMolecular Weight:397.70Molecular Formula:C16H10F6NO2Solubility:Soluble in DMSO (up to at least 25 mg/ml) and Ethanol (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
SX-682 | CXCR1/2 inhibitor
From $90.00CAS:1648843-04-2Catalog Number:10-4925Activity:CXCR1/2 inhibitorChemical Names:[2-[[5-[(4-Fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acidMolecular Weight:467.20Molecular Formula:C19H14BF4N3O4SSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
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- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
