Immuno-oncology
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Epacadostat | IDO1 inhibitor
From $45.00CAS:1204669-58-8Catalog Number:10-4499Activity:IDO1 inhibitor/ Cancer immunotherapy enhancerChemical Name:N-(3-Bromo-4-fluorophenyl)-N’-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamideAlternate Name:INCB024360Molecular Weight:438.23Molecular Formula:C11H13BrFN7O4SSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Everolimus | mTOR inhibitor
From $55.00CAS:159351-69-6Catalog Number:10-2136Activity:mTOR inhibitorAlternate Names:SDZ RAD; RAD001Chemical Name:40-O-(2-Hydroxyethyl)rapamycinMolecular Weight:958.25Molecular Formula:C53H84NO14Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic
From $45.00CAS:700874-72-2Catalog Number:10-4110Activity:Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeuticChemical Name:4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamideAlternate Names:LY2157299Molecular Weight:369.43Molecular Formula:C22H19N5OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Ganetespib | HSP90 inhibitor
From $60.00CAS:888216-25-9Catalog Number:10-4474Activity:HSP90 inhibitorChemical Name:3-(2,4-Dihydroxy-5-propan-2-ylphenyl)-4-(1-methylindol-5-yl)-1H-1,2,4-triazol-5-one;
Molecular Weight:364.40Molecular Formula:C20H20N4O3Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:>98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
