Immuno-oncology
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PD-1/PD-L1 Inhibitor 1
From $95.00CAS:1675201-83-8Catalog Number:10-4901Activity:PD-1/PD-L1 inhibitorChemical Name:(2S)-1-[[2,6-Dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]pipieridine-2-carboxylic acidAlternate Name:BMS-3Molecular Weight:475.59Molecular Formula:C29H33N2O5Solubility:Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Pexidartinib | CSF1R inhibitor
From $45.00CAS:1029044-16-3Catalog Number:10-4829Activity:CSF1R inhibitor/Cancer immunotherapy enhancerChemical Name:5-[(5-Chloro-1H-pyrrolo[2,3.b]pyridine-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amineAlternate Names:PLX3397Molecular Weight:417.81Molecular Formula:C20H15ClF3N5Solubility:Soluble in DMSO (up to at least 10 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
PF-06840003 | IDO1 inhibitor
From $60.00CAS:198474-05-4Catalog Number:10-4498Activity:IDO1 inhibitor/Cancer immunotherapy enhancerChemical Name:3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dioneAlternate Name:EOS200271Molecular Weight:232.21Molecular Formula:C12H9FN2O2Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
PF-4136309 | CCR2 antagonist
From $75.00CAS:1341224-83-6Catalog Number:10-4261Activity:CCR2 antagonistChemical Name:N-[2-[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamideAlternate Name:INCB8761Molecular Weight:568.60Molecular Formula:C29H31F3N6O3Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Preladenant | Potent and selective adenosine A2A antagonist
From $70.00CAS:377727-87-2Catalog Number:10-4102Chemical Name:4-(Furan-2-yl)-10-[2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]ethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amineAlternate Name:SCH 420814Molecular Weight:503.57Molecular Formula:C29H29N9O3Solubility:Soluble in DMSO (up to 5 mg/ml with warming).Physical Properties:Beige solidPurity:>98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
