Kinases Archives

Fruquintinib | Potent and selective inhibitor of VEGFR kinase

CAS:

1194506-26-7

Catalog Number:

10-4784

Activity:

Potent and selective inhibitor of VEGFR kinase

Chemical Name:

6-(6,7-Dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide

Alternate Name:

HMPL-013

Molecular Weight:

393.40

Molecular Formula:

C₂₁H₁₉N₃O₅

Solubility:

Soluble in DMSO (up to 5 mg/ml).

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $60.00
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Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic

CAS:

700874-72-2

Catalog Number:

10-4110

Activity:

Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeutic

Chemical Name:

4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide

Alternate Names:

LY2157299

Molecular Weight:

369.43

Molecular Formula:

C₂₂H₁₉N₅O

Solubility:

Soluble in DMSO (up to 25 mg/ml)

Physical Properties:

White solid

Purity:

98%
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $45.00
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GDC-0941 | pan-PI3K inhibitor

CAS:

957054-30-7

Catalog Number:

10-2141

Activity:

pan-Class I PI3-kinase inhibitor

Chemical Names:

4-[2-(1H-Indazol-4-yl)-6-[(4-methylsulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine; Pictilisib

Molecular Weight:

513.64

Molecular Formula:

C₂₃H₂₇N₇O₃S₂

Solubility:

Soluble in DMSO (>25 mg/ml)

Physical Properties:

White/off-white solid

Purity:

99% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $58.00
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Gefitinib | EGFR kinase inhibitor

CAS:

184475-35-2

Catalog Number:

10-1148

Activity:

EGFR-Kinase inhibitor

Alternate Names:

ZD1839, Iressa

Chemical Name:

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

Molecular Weight:

446.91

Molecular Formula:

C₂₂H₂₄ClFN₄O₃

Solubility:

Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml).

Physical Properties:

Tan solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

RT

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $30.00
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Genistein | Genistin aglycone

CAS:

446-72-0

Catalog Number:

10-2139

Activity:

Tyrosine kinase inhibitor

Chemical Name:

5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Alternate Names:

4’,5,7-Trihydroxyisoflavone

Molecular Weight:

270.24

Molecular Formula:

C₁₅H₁₀O₅

Solubility:

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 4 mg/ml)

Physical Properties:

Yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 week.

Shipping Code:

RT

From $30.00
View Product This product has multiple variants. The options may be chosen on the product page

Kinases

Fruquintinib | Potent and selective inhibitor of VEGFR kinase

Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic

GDC-0941 | pan-PI3K inhibitor

Gefitinib | EGFR kinase inhibitor

Genistein | Genistin aglycone

EXPLORE OTHER Cancer

20% OFF

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

Fruquintinib | Potent and selective inhibitor of VEGFR kinase

Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic

GDC-0941 | pan-PI3K inhibitor

Gefitinib | EGFR kinase inhibitor

Genistein | Genistin aglycone

EXPLORE OTHER Cancer

20% OFF

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21