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Kinases

  • Flavopiridol HCl | CDK inhibitor

    CAS:
    131740-09-5
    Catalog Number:
    10-3063
    Activity:
    CDK inhibitor
    Chemical Name:
    3-(3-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, hydrochloride
    Alternate Names:
    L 86-8275; Alvocidib; NSC-649890
    Molecular Weight:
    438.30
    Molecular Formula:
    C21H20ClNO5 &bul; HCl
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Water (up to 40 mg/ml).
    Physical Properties:
    Light yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month
    Shipping Code:
    RT
    From $50.00
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  • Fruquintinib | Potent and selective inhibitor of VEGFR kinase

    CAS:
    1194506-26-7
    Catalog Number:
    10-4784
    Activity:
    Potent and selective inhibitor of VEGFR kinase
    Chemical Name:
    6-(6,7-Dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide
    Alternate Name:
    HMPL-013
    Molecular Weight:
    393.40
    Molecular Formula:
    C21H19N3O5
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic

    CAS:
    700874-72-2
    Catalog Number:
    10-4110
    Activity:
    Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeutic
    Chemical Name:
    4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
    Alternate Names:
    LY2157299
    Molecular Weight:
    369.43
    Molecular Formula:
    C22H19N5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • GDC-0941 | pan-PI3K inhibitor

    CAS:
    957054-30-7
    Catalog Number:
    10-2141
    Activity:
    pan-Class I PI3-kinase inhibitor
    Chemical Names:
    4-[2-(1H-Indazol-4-yl)-6-[(4-methylsulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine; Pictilisib
    Molecular Weight:
    513.64
    Molecular Formula:
    C23H27N7O3S2
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White/off-white solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $58.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Gefitinib | EGFR kinase inhibitor

    CAS:
    184475-35-2
    Catalog Number:
    10-1148
    Activity:
    EGFR-Kinase inhibitor
    Alternate Names:
    ZD1839, Iressa
    Chemical Name:
    N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
    Molecular Weight:
    446.91
    Molecular Formula:
    C22H24ClFN4O3
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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