Kinases

  • Hypothemycin | MEK inhibitor

    CAS:
    76958-67-3
    Catalog Number:
    10-2483
    Activity:
    MEK inhibitor
    Source:
    Natural product isolated from Phoma sp.
    Molecular Weight:
    378.37
    Molecular Formula:
    C19H22O8
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >96% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    $200.00
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  • Ibrutinib | BTK inhibitor

    CAS:
    936563-96-1
    Catalog Number:
    10-4757
    Alternate Name:
    PCI-32765
    Activity:
    BTK inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
    Molecular Weight:
    440.51
    Molecular Formula:
    C25H24N6O2
    Solubility:
    Soluble in DMSO ( up to at least 25 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Idelalisib | Selective PI3Kδ Inhibitor

    CAS:
    870281-82-6
    Catalog Number:
    10-4820
    Activity:
    Selective PI3Kδ Inhibitor
    Chemical Name:
    5-Fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
    Alternate Names:
    CAL-101
    Molecular Weight:
    415.43
    Molecular Formula:
    C21H18FN7O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • Imatinib mesylate | BCR-ABL inhibitor

    CAS:
    220127-57-1
    Catalog Number:
    10-1060
    Activity:
    BCR-ABL inhibitor
    Alternate Names:
    Gleevec
    Chemical Name:
    4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
    Molecular Weight:
    589.73
    Molecular Formula:
    C29H31N7O CH3SO3H
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Indirubin-3′-monoxime | GSK-3ß and CDK inhibitor

    CAS:
    160807-49-8
    Catalog Number:
    10-1488
    Activity:
    GSK-3β and CDK inhibitor
    Alternate Names:
    Indirubin-3’oxime
    Chemical Name:
    3-[1,3-Dihydro-3-(hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
    Molecular Weight:
    277.29
    Molecular Formula:
    C16H11N3O2
    Solubility:
    Soluble in DMSO (up to 6 mg/ml) or in Ethanol (up to 4 mg/ml).
    Physical Properties:
    Dark red or brown solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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