Kinases

  • GSK2636771 | Potent and selective inhibitor of PI3Kß

    CAS:
    1372540-25-4
    Catalog Number:
    10-4172
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  • GSK2656157 | PERK inhibitor

    CAS:
    1337532-29-2
    Catalog Number:
    10-4855
    Activity:
    PERK inhibitor
    Chemical Names:
    1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
    Molecular Weight:
    416.45
    Molecular Formula:
    C23H21FN6O
    Solubility:
    Soluble in DMSO (10 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Hypothemycin | MEK inhibitor

    CAS:
    76958-67-3
    Catalog Number:
    10-2483
    Activity:
    MEK inhibitor
    Source:
    Natural product isolated from Phoma sp.
    Molecular Weight:
    378.37
    Molecular Formula:
    C19H22O8
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >96% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    $200.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Ibrutinib | BTK inhibitor

    CAS:
    936563-96-1
    Catalog Number:
    10-4757
    Alternate Name:
    PCI-32765
    Activity:
    BTK inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
    Molecular Weight:
    440.51
    Molecular Formula:
    C25H24N6O2
    Solubility:
    Soluble in DMSO ( up to at least 25 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Idelalisib | Selective PI3Kδ Inhibitor

    CAS:
    870281-82-6
    Catalog Number:
    10-4820
    Activity:
    Selective PI3Kδ Inhibitor
    Chemical Name:
    5-Fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
    Alternate Names:
    CAL-101
    Molecular Weight:
    415.43
    Molecular Formula:
    C21H18FN7O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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