Kinases
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Lapatinib (base) | EGFR and HER2 inhibitor
From $55.00CAS:231277-92-2Catalog Number:10-2147Activity:EGFR and HER2 inhibitorChemical Name:N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amineAlternate Names:GW-572016Molecular Weight:581.06Molecular Formula:C29H26ClFN4O4SSolubility:Soluble in DMSO (up to 200 mg/ml)Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Larotrectinib | TRK inhibitor
From $60.00CAS:1223403-58-4Catalog Number:10-4832Activity:Potent and selective panTRK inhibitorChemical Name:(3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)pyrrolidine-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamideAlternate Name:LOXO-101; ARRY-470Molecular Weight:428.44Molecular Formula:C21H22F2N5O2Solubility:Soluble in DMSO (up to 5 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.Shipping Code:RT -
LDN-192960 2HCl | Haspin and DYRK2/3 inhibitor
From $55.00CAS:184582-62-5Catalog Number:10-4836Activity:Haspin and DYRJ2/3 inhibitorChemical Names:3-(2,7-Dimethoxyacridin-9-yl)sulfanylpropan-1-amine dihydrochlorideMolecular Weight:401.35Molecular Formula:C18H20N2O2S·2HClSolubility:Soluble in DMSO (>25 mg/ml); Water (2 mg/ml)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Lenvatinib | VEGFR inhibitor
From $55.00CAS:417716-92-8Catalog Number:10-3313Activity:VEGFR inhibitorChemical Name:4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamideAlternate Names:E7080Molecular Weight:426.85Molecular Formula:C21H19ClN4O4Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
