Kinases
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Linsitinib | Inhibits IGF-1R kinase and InsR kinase
From $60.00CAS:867160-71-2Catalog Number:10-4814Activity:Inhibits IGF-1R kinase and InsR kinaseChemical Name:3-[8-Amino-1-(2-phenyl-7-quinolyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanolAlternate Names:OSI-906Molecular Weight:421.49Molecular Formula:C26H23N5OSolubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
LY-364947 | ALK5 inhibitor
From $75.00CAS:396129-53-6Catalog Number:10-1492Activity:ALK5 inhibitorAlternate Names:HTS-466284Chemical Name:4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinoloneMolecular Weight:272.31Molecular Formula:C17H12N4Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Brown solidPurity:98% by TLCStorage Temperature:RT (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
LY2603618 | Potent and selective Chk1 inhibitor
From $50.00CAS:911222-45-2Catalog Number:10-4123Activity:Potent and selective Chk1 inhibitorChemical Name:N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N’-(5-methyl-2-pyrazinyl)ureaAlternate Names:RabusertibMolecular Weight:436.30Molecular Formula:C18H22BrN5O3Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Meleagrin | Met inhibitor, anticancer activity
From $145.00CAS:71751-77-4Catalog Number:10-1599Activity:Met inhibitor, anticancer activityChemical Name:(3E,7aR,12aS-7a-(1,1-Dimethyl-2-propen-1-yl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-5-ylmethylene)-12-methoxy-1H,5H-imidazol[1’,2’:1,2]pyrido[2,3-b]indole-2,5(3H)-dioneMolecular Weight:433.46Molecular Formula:C23H23N5O4Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:Tan solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
MK-2206 | Potent and selective AKT inhibitor
From $60.00CAS:1032350-13-2Catalog Number:10-4801Activity:Potent and selective AKT inhibitorChemical Name:8-(4-(1-Aminocyclobutyl)phenyl-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one dihydrochlorideMolecular Weight:480.39Molecular Formula:C25H21N5O • 2HClSolubility:Soluble in DMSO (up to 10 mg/ml with warming)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
