Kinases Archives

BI 2536 | Dual Plk/BRD4 inhibitor – Destabilizes Myc

CAS:

755038-02-9

Catalog Number:

10-4121

Activity:

Dual Plk/BRD4 inhibitor – Destabilizes Myc

Chemical Name:

4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide

Molecular Weight:

521.67

Molecular Formula:

C₂₈H₃₉N₇O₃

Solubility:

Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 25 mg/ml)

Physical Properties:

Off-white solid

Purity:

97% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $75.00
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BI-D1870 | p90 ribosomal S6 kinase inhibitor

CAS:

501437-28-1

Catalog Number:

10-4791

Activity:

p90 ribosomal S6 kinase inhibitor

Chemical Name:

2-(3,5-Difluoro-4-hydroxyanilino)-5,7-dimethyl-8-(3-methylbutyl)-7H-pteridin-6-one

Molecular Weight:

391.42

Molecular Formula:

C₁₉H₂₃F₂N₅O₂

Solubility:

Soluble in DMSO (up to 15 mg/ml)

Physical Properties:

Off-white solid

Purity:

98%
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $90.00
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Binimetinib | MEK1/2 inhibitor

CAS:

606143-89-9

Catalog Number:

10-4789

Activity:

MEK1/2 inhibitor

Chemical Name:

6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide

Alternate Names:

ARRY-162; MEK162

Molecular Weight:

441.23

Molecular Formula:

C₁₇H₁₅BrF₂N₄O₃

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $39.00
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BML283 | PKM2 activator

CAS:

562867-96-3

Catalog Number:

10-4561

Activity:

PKM2 activator

Alternate Names:

ML083

Chemical Name:

1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)-4-(4-methoxyphenylsulfonyl)piperazine

Molecular Weight:

454.51

Molecular Formula:

C₁₉H₂₂N₂O₇S₂

Solubility:

Soluble in DMSO (up to 10 mg/ml).

Physical Properties:

White solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

Shipping Code:

RT

From $45.00
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Bosutinib | Dual Src/Abl kinase inhibitor

CAS:

380843-75-4

Catalog Number:

10-2122

Activity:

Dual Src/Abl kinase inhibitor

Chemical Names:

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile

Alternate Name:

SKI-606

Molecular Weight:

530.45

Molecular Formula:

C₂₆H₂₉Cl₂N₅O₃

Solubility:

Soluble in DMSO (100 mg/ml); Ethanol (up to 25 mg/ml with warming)

Physical Properties:

Off-white solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $40.00
View Product This product has multiple variants. The options may be chosen on the product page

Kinases

BI 2536 | Dual Plk/BRD4 inhibitor – Destabilizes Myc

BI-D1870 | p90 ribosomal S6 kinase inhibitor

Binimetinib | MEK1/2 inhibitor

BML283 | PKM2 activator

Bosutinib | Dual Src/Abl kinase inhibitor

EXPLORE OTHER Cancer

20% OFF

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

BI 2536 | Dual Plk/BRD4 inhibitor – Destabilizes Myc

BI-D1870 | p90 ribosomal S6 kinase inhibitor

Binimetinib | MEK1/2 inhibitor

BML283 | PKM2 activator

Bosutinib | Dual Src/Abl kinase inhibitor

EXPLORE OTHER Cancer

20% OFF

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21