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Kinases

  • Cabozantinib chemical structure

    Cabozantinib | Met and VEGFR2 inhibitor

    CAS:
    849217-68-1
    Catalog Number:
    10-3231
    Activity:
    Met and VEGFR2 inhibitor
    Chemical Name:
    N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Alternate Names:
    XL-184; BMS-907351; Carbozantinib
    Molecular Weight:
    501.51
    Molecular Formula:
    C28H24FN3O5
    Solubility:
    Soluble in DMSO
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • CDD-2789 chemical structure

    CDD-2789 | ALK1/2 inhibitor

    CAS:
    3052084-77-9
    Catalog Number:
    10-4451
    View Product This product has multiple variants. The options may be chosen on the product page

  • CID-2011756 | PKD inhibitor

    CAS:
    638156-11-3
    Catalog Number:
    10-1420
    Activity:
    PKD inhibitor
    Chemical Name:
    5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide
    Molecular Weight:
    396.88
    Molecular Formula:
    C22H21ClN2O3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 8 mg/ml with warming).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Crenolanib | PDGFR and FLT3 inhibitor

    CAS:
    670220-88-9
    Catalog Number:
    10-4782
    Activity:
    PDGFR and FLT3 inhibitor
    Chemical Name:
    1-[2-[5-[(3-Methyloxetan-3-yl)methoxy]benzimidazole-1-yl]quinoline-8-yl]piperidin-4-amine
    Alternate Name:
    CP-868,596
    Molecular Weight:
    443.55
    Molecular Formula:
    C26H29N5O2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Crizotinib | c-MET and ALK inhibitor

    CAS:
    877399-52-5
    Catalog Number:
    10-2626
    Activity:
    c-MET and ALK inhibitor
    Chemical Name:
    3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
    Alternate Names:
    PF-02341066, PF-1066
    Molecular Weight:
    450.34
    Molecular Formula:
    C21H22Cl2FN5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Plymouth Meeting, PA USA
1-855-FOCUS21

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