Kinases
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Defactinib | Potent FAK inhibitor
From $65.00CAS:1073154-85-4Catalog Number:10-4828Activity:Potent FAK inhibitorChemical Name:N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamideMolecular Weight:510.50Molecular Formula:C20H21F3N8O3SSolubility:Soluble in DMSO (up to at least 25mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dovitinib | Multi-kinase inhibitor
From $75.00CAS:405169-16-6Catalog Number:10-2129Activity:Kinase inhibitorAlternate Names:TKI-258, CHIR258Chemical Name:4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-oneMolecular Weight:392.43Molecular Formula:C21H21FN6OSolubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:Yellow-green solidPurity:99% by TLC
99% by HPLCStorage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
DRB | Transcription inhibitor/CK2 inhibitor
From $27.00CAS:53-85-0Catalog Number:10-2047Activity:Transcription inhibitor, CK2 inhibitorChemical Name:5,6-Dichloro-1-β-D-ribofuranosylbenzimidazoleAlternate Names:5,6-Dichlorobenzimidazole riboside; NSC 401575Molecular Weight:319.14Molecular Formula:C12H12Cl2N2O4Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dubermatinib | AXL inhibitor
CAS:1341200-45-0Catalog Number:10-4679 -
Duvelisib | PI3Kdelta/gamma inhibitor
From $65.00CAS:1201438-56-3Catalog Number:10-4788Activity:PI3Kδ/γ inhibitor/Cancer immunotherapy enhancerChemical Name:8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-oneAlternative Name:IPI-145Molecular Weight:416.87Molecular Formula:C22H17ClN6OSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
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- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
