Kinases
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Dabrafenib | B-Raf mutant inhibitor
From $40.00CAS:1195765-45-7Catalog Number:10-1569Activity:B-Raf mutant inhibitorChemical Name:N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamideAlternate Names:GSK2118436Molecular Weight:519.56Molecular Formula:C23H20F3N5O2SSolubility:Soluble in DMSO (up to 30 mg/ml with warming), or in Ethanol (up to 1 mg/ml with warming).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Defactinib | Potent FAK inhibitor
From $65.00CAS:1073154-85-4Catalog Number:10-4828Activity:Potent FAK inhibitorChemical Name:N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamideMolecular Weight:510.50Molecular Formula:C20H21F3N8O3SSolubility:Soluble in DMSO (up to at least 25mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dovitinib | Multi-kinase inhibitor
From $75.00CAS:405169-16-6Catalog Number:10-2129Activity:Kinase inhibitorAlternate Names:TKI-258, CHIR258Chemical Name:4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-oneMolecular Weight:392.43Molecular Formula:C21H21FN6OSolubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:Yellow-green solidPurity:99% by TLC
99% by HPLCStorage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
DRB | Transcription inhibitor/CK2 inhibitor
From $27.00CAS:53-85-0Catalog Number:10-2047Activity:Transcription inhibitor, CK2 inhibitorChemical Name:5,6-Dichloro-1-β-D-ribofuranosylbenzimidazoleAlternate Names:5,6-Dichlorobenzimidazole riboside; NSC 401575Molecular Weight:319.14Molecular Formula:C12H12Cl2N2O4Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
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- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
