Programmed cell death
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Nutlin-3 | p53/mdm2 inhibitor
From $100.00CAS:548472-68-0Catalog Number:10-1350Activity:p53/mdm2 inhibitorChemical Name:(±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-oneMolecular Weight:581.51Molecular Formula:C30H30Cl2N4O4Solubility:Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
Obatoclax | Bcl-2 antagonist – Induces apoptosis
From $70.00CAS:803712-79-0Catalog Number:10-2660Activity:BCL-2 antagonist – Induces apoptosisAlternate Names:GX15-070Chemical Name:2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonateMolecular Weight:413.5Molecular Formula:C20H19N3O CH3SO3HSolubility:Soluble in DMSO (up to 5 mg/ml).Physical Properties:Purple solidPurity:98% by TLCStorage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Ophiobolin A | Autophagy inducer / Anticancer
From $60.00CAS:4611-05-6Catalog Number:10-3150Activity:Autophagy inducer / AnticancerAlternate Names:Cochliobolin A; Ophiobalin; NSC 114340Molecular Weight:400.55Molecular Formula:C25H36O4Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Oridonin | Inflammasome inhibitor
From $40.00CAS:28957-04-2Catalog Number:10-2616Activity:HSP70 inhibitorChemical Name:7a,20-Epoxy-1a,6b,7,14-tetrahydroxykaur-16-en-15-oneAlternate Name:IsodonolMolecular Weight:364.43Molecular Formula:C20H28O6Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml with warming).Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20° (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
