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Programmed cell death

  • NSC697923 | E2 ubiquitin-conjugating enzyme inhibitor

    CAS:
    343351-67-7
    Catalog Number:
    10-1418
    Activity:
    Ubiquitin E2 conjugating enzyme inhibitor
    Chemical Name:
    2-[(Methylphenyl)sulfonyl]-5-nitrofuran
    Molecular Weight:
    267.26
    Molecular Formula:
    C11H9NO5S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
    Physical Properties:
    Pink solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Nutlin-3 | p53/mdm2 inhibitor

    CAS:
    548472-68-0
    Catalog Number:
    10-1350
    Activity:
    p53/mdm2 inhibitor
    Chemical Name:
    (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
    Molecular Weight:
    581.51
    Molecular Formula:
    C30H30Cl2N4O4
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $100.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Obatoclax | Bcl-2 antagonist – Induces apoptosis

    CAS:
    803712-79-0
    Catalog Number:
    10-2660
    Activity:
    BCL-2 antagonist – Induces apoptosis
    Alternate Names:
    GX15-070
    Chemical Name:
    2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate
    Molecular Weight:
    413.5
    Molecular Formula:
    C20H19N3O CH3SO3H
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    Purple solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Ophiobolin A | Autophagy inducer / Anticancer

    CAS:
    4611-05-6
    Catalog Number:
    10-3150
    Activity:
    Autophagy inducer / Anticancer
    Alternate Names:
    Cochliobolin A; Ophiobalin; NSC 114340
    Molecular Weight:
    400.55
    Molecular Formula:
    C25H36O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Oridonin | Inflammasome inhibitor

    CAS:
    28957-04-2
    Catalog Number:
    10-2616
    Activity:
    HSP70 inhibitor
    Chemical Name:
    7a,20-Epoxy-1a,6b,7,14-tetrahydroxykaur-16-en-15-one
    Alternate Name:
    Isodonol
    Molecular Weight:
    364.43
    Molecular Formula:
    C20H28O6
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml with warming).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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