Programmed cell death

  • ABT-263 | Bcl-2 family inhibitor; Senolytic agent

    CAS:
    923564-51-6
    Catalog Number:
    10-3141
    Activity:
    Bcl-2 family inhibitor; Senolytic agent
    Chemical Name:
    4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)- 3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]-benzamide
    Alternate Name:
    Navitoclax
    Molecular Weight:
    974.61
    Molecular Formula:
    C47H55ClF3N5O6S3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • ABT-737 | Senolytic Bcl2 inhibitor

    CAS:
    852808-04-9
    Catalog Number:
    10-3661
    Activity:
    Senolytic Bcl inhibitor
    Chemical Names:
    4-[4-[(4′-Chloro[1,1′-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]-benzamide
    Molecular Weight:
    813.43
    Molecular Formula:
    C42H45ClN6O5S2
    Solubility:
    Soluble in DMSO (5 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Adapalene | Retinoid RARbeta, gamma agonist

    CAS:
    106685-40-9
    Catalog Number:
    10-1011
    Activity:
    Retinoid RARβ,γ agonist
    Alternate Names:
    CD271
    Chemical Name:
    6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid
    Molecular Weight:
    412.53
    Molecular Formula:
    C28H28O3
    Solubility:
    Soluble in DMSO (up to 3 mg/ml) or in DMF (up to 6 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • AG-1296 | PDGFR kinase inhibitor

    CAS:
    146535-11-7
    Catalog Number:
    10-1087
    Activity:
    PDGFR kinase inhibitor
    Chemical Name:
    6,7-Dimethoxy-3-phenylquinoxaline
    Molecular Weight:
    266.3
    Molecular Formula:
    C16H14N2O2
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Altretamine | Ferroptosis inducer

    CAS:
    645-05-6
    Catalog Number:
    10-5592
    Activity:
    Ferroptosis inducer/GPX4 inhibitor
    Chemical Names:
    N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 2,4,6-Tris(dimethylamino)-1,3,5-triazine
    Alternate Name:
    Hexamethylmelamine; NSC-13875
    Molecular Weight:
    210.29
    Molecular Formula:
    C9H18N6
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $35.00
    View Product This product has multiple variants. The options may be chosen on the product page
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