Programmed cell death Archives

Vismodegib | Sonic Hedgehog signaling pathway inhibitor

CAS:

879085-55-9

Catalog Number:

10-2182

Activity:

Sonic Hedgehog signaling pathway inhibitor

Chemical Name:

2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide

Alternate Names:

GDC-0449

Molecular Weight:

421.3

Molecular Formula:

C₁₉H₁₄Cl₂N₂O₃S

Solubility:

Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 10 mg/ml with warming)

Physical Properties:

Off-white or beige solid

Purity:

99% by TLC and HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $60.00
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WHI-P131 | JAK3 inhibitor

CAS:

202475-60-3

Catalog Number:

10-1190

Activity:

JAK3 inhibitor

Alternate Names:

JANEX-1

Chemical Name:

4-[(4′-Hydroxyphenyl)amino]-6,7-dimethoxyquinazoline

Molecular Weight:

333.78

Molecular Formula:

C₁₆H₁₅N₃O₃·HCl

Solubility:

Soluble in DMSO (up to 50 mg/ml).

Physical Properties:

Yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $60.00
View Product This product has multiple variants. The options may be chosen on the product page
WP1066 | JAK2/STAT3 inhibitor

CAS:

857064-38-1

Catalog Number:

10-4831

Activity:

JAK2/STAT3 inhibitor

Chemical Name:

(E)-3-(6-Pyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide

Molecular Weight:

356.22

Molecular Formula:

C₁₇H₁₄BrN₃O

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $79.00
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WP1130 | DUB inhibitor

CAS:

856243-80-6

Catalog Number:

10-1351

Activity:

DUB inhibitor

Alternate Names:

Degrasyn

Chemical Name:

(S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide

Molecular Weight:

384.28

Molecular Formula:

C₁₉H₁₈BrN₃O

Solubility:

Soluble in DMSO (up to 45 mg/ml), or in Ethanol (up to 25 mg/ml).

Physical Properties:

Yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $55.00
View Product This product has multiple variants. The options may be chosen on the product page
WP631 | SP-1 activated transcription inhibitor

CAS:

Not available

Catalog Number:

10-3497

Activity:

SP-1 activated transcription inhibitor

Chemical Names:

4-Methylbenzyl-N-bis[daunomycin], mesylate salt

Molecular Weight:

1349.38

Molecular Formula:

C₆₂H₆₄N₂O₂₀ ∙ 2CH₃SO₃H

Solubility:

Soluble in DMSO (up to 5 mg/ml)

Physical Properties:

Red solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C (des,)

Stability:

Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $65.00
View Product This product has multiple variants. The options may be chosen on the product page

Programmed cell death

Vismodegib | Sonic Hedgehog signaling pathway inhibitor

WHI-P131 | JAK3 inhibitor

WP1066 | JAK2/STAT3 inhibitor

WP1130 | DUB inhibitor

WP631 | SP-1 activated transcription inhibitor

EXPLORE OTHER Cancer

20% OFF

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Programmed cell death

Vismodegib | Sonic Hedgehog signaling pathway inhibitor

WHI-P131 | JAK3 inhibitor

WP1066 | JAK2/STAT3 inhibitor

WP1130 | DUB inhibitor

WP631 | SP-1 activated transcription inhibitor

EXPLORE OTHER Cancer

20% OFF

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21