DNA Damage Response
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TH588 | MTH1/NUDT1 inhibitor
From $65.00CAS:1609960-31-7 (free base)Catalog Number:10-4602Activity:MTH1/NUDT1 inhibitorChemical Name:N4-Cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine hydrochlorideMolecular Weight:331.63Molecular Formula:C13H12Cl2N4 · HClSolubility:Soluble in DMSO (up to 5 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
UPF-1069 | PARP-2 inhibitor
From $55.00CAS:1048371-03-4Catalog Number:10-3779Activity:PPAR-2 inhibitorChemical Name:5-(2-Oxo-3-phenylethoxy)-1(2H)-isoquinolinoneMolecular Weight:279.29Molecular Formula:C17H13NO3Solubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
VE-821 | Potent and selective ATR inhibitor
From $80.00CAS:1232410-49-9Catalog Number:10-5589Activity:ATR inhibitorChemical Names:3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamideMolecular Weight:368.41Molecular Formula:C18H16N4O3SSolubility:Soluble in DMSO (40 mg/ml)Physical Properties:Beige solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
YM-155 | Survivin inhibitor
From $58.00CAS:781661-94-7Catalog Number:10-1473Activity:Survivin inhibitorAlternate Names:Sepantronium bromideChemical Name:1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromideMolecular Weight:443.3Molecular Formula:C20H19BrN4O3Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Tan to yellow solidPurity:>98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
