DNA Damage Response

  • Gemcitabine HCl | DNA polymerase inhibitor

    CAS:
    122111-03-9
    Catalog Number:
    10-2140
    Activity:
    DNA polymerase inhibitor
    Alternate Names:
    dFdC
    Chemical Name:
    2′-Deoxy-2′,2′-difluorocytidine hydrochloride
    Molecular Weight:
    299.66
    Molecular Formula:
    C9H11F2N3O4 HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
  • GPI-16552 | PARG inhibitor

    CAS:
    443794-40-9
    Catalog Number:
    10-1502
    Activity:
    PARG inhibitor
    Chemical Name:
    N-bis-(3-Phenyl-propyl)-9-oxo-fluorene-2,7-diamide
    Molecular Weight:
    502.62
    Molecular Formula:
    C33H30N2O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in DMF (up to 25 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • IMP-1700 | Bacterial DNA repair inhibitor

    CAS:
    1458674-25-3
    Catalog Number:
    10-3950
    Activity:
    Bacterial DNA repair inhibitor
    Chemical Name:
    1-Cyclopropyl-6-fluoro-4-oxo-7-(4-(4-(trifluoromethyl)phenyl)carbamothioyl)piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid
    Molecular Weight:
    534.53
    Molecular Formula:
    C25H22F4N4O5S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
  • Iniparib

    CAS:
    160003-66-7
    Catalog Number:
    10-2574
    Activity:
    PARP inhibitor
    Chemical Name:
    4-Iodo-3-nitrobenzamide
    Alternate Names:
    BSI-201
    Molecular Weight:
    292.03
    Molecular Formula:
    C7H5IN2O3
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or Ethanol (up to 15 mg/ml
    Physical Properties:
    Yellow solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
  • KU-55933 | ATM Kinase Inhibitor

    CAS:
    587871-26-9
    Catalog Number:
    10-1518
    Activity:
    ATM Kinase Inhibitor
    Chemical Name:
    2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one
    Molecular Weight:
    395.5
    Molecular Formula:
    C21H17NO3S2
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $65.00
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