DNA Damage Response

  • AZ20 | ATR kinase inhibitor

    CAS:
    1233339-22-4
    Catalog Number:
    10-4675
    Activity:
    ATR kinase inhibitor
    Chemical Name:
    4-{4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl}-1H-indole
    Molecular Weight:
    412.51
    Molecular Formula:
    C21H24N4O3S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $55.00
  • BML-277 | CHK2 inhibitor

    CAS:
    516480-79-8
    Catalog Number:
    10-1024
    Activity:
    CHK2 inhibitor
    Chemical Name:
    2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
    Molecular Weight:
    363.81
    Molecular Formula:
    C20H14ClN3O2
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR conforms
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • Doxorubicin HCl | DNA damaging agent

    CAS:
    25316-40-9
    Catalog Number:
    10-2130
    Activity:
    DNA damaging agent
    Alternate Names:
    Adriamycin; NSC-123127
    Molecular Weight:
    579.99
    Molecular Formula:
    C27H29NO11 HCl
    Solubility:
    Soluble in Water (up to 25 mg/ml).
    Physical Properties:
    Red-orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • Epirubicin HCl | DNA damaging agent

    CAS:
    56390-09-1
    Catalog Number:
    10-2761
    Activity:
    DNA damaging agent
    Chemical Name:
    4′-Epidoxorubicin
    Molecular Weight:
    579.99
    Molecular Formula:
    C27H29NO11 HCl
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 5 mg/ml).
    Physical Properties:
    Red orange solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $48.00
  • Etoposide | Topoisomerase II inhibitor

    CAS:
    33419-42-0
    Catalog Number:
    10-1123
    Activity:
    Topoisomerase II inhibitor
    Chemical Name:
    4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-ß-D-glucopyranoside
    Molecular Weight:
    588.56
    Molecular Formula:
    C29H32O13
    Solubility:
    Soluble in DMSO (up to 30 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
    Shipping Code:
    RT
    From $50.00
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