DNA Damage Response
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Mitomycin C | DNA crosslinking and damaging agent
From $55.00CAS:50-07-7Catalog Number:10-1170Activity:DNA crosslinking and damaging agentChemical Name:Natural fermentation product from Streptomyces sp.Molecular Weight:334.33Molecular Formula:C15H18N4O5Solubility:Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).Physical Properties:Blue-violet solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.Shipping Code:RT -
NU7441 | DNA-PK inhibitor
From $50.00CAS:503468-95-9Catalog Number:10-4810Activity:DNA-PK inhibitorChemical Name:8-Dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-oneAlternate Name:Ku-57788Molecular Weight:413.49Molecular Formula:C25H19NO3SSolubility:Soluble in DMSO (up to 10 mg/ml with warming).Physical Properties:Off-white to beige solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Olaparib | PARP1 inhibitor
From $45.00CAS:763113-22-0Catalog Number:10-2154Activity:PARP1 inhibitorChemical Name:4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-oneAlternate Names:AZD-2281; KU-59436Molecular Weight:434.47Molecular Formula:C24,/sub>H23,/sub>FN<sub.4< sub=””>O3</sub.4<>Solubility:Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
PJ-34 HCl | PARP1/2 inhibitor
From $56.00CAS:344458-15-7Catalog Number:10-2395Activity:PARP1,2 inhibitorChemical Name:N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochlorideMolecular Weight:331.81Molecular Formula:C17H17N3O2Solubility:Soluble in DMSO (up to 30 mg/ml) or in Water (up to 20 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RT (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
RI-1 | RAD51 inhibitor
From $52.00CAS:415713-60-9Catalog Number:10-1617Activity:RAD51 inhibitorChemical Name:3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dioneMolecular Weight:361.61Molecular Formula:C14H11Cl3N2O3Solubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 10 mg/ml with warming)Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT
