ER Stress

  • Nelfinavir mesylate | HIV protease inhibitor / Anticancer activity

    CAS:
    159989-65-8
    Catalog Number:
    10-3050
    Activity:
    HIV protease inhibtior / Anticancer activity
    Chemical Name:
    (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide methanesulfonate
    Alternate Name:
    AG-1343
    Molecular Weight:
    663.88
    Molecular Formula:
    C32H45N3O4S • CH3SO3H
    Solubility:
    Soluble in DMSO (up to 70 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • Patulin | Oxidative- and ER-stress inducer

    CAS:
    149-29-1
    Catalog Number:
    10-2097
    Activity:
    Oxidative- and ER-stress inducer
    Chemical Name:
    4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
    Alternate Names:
    Clavacin, Mycoin, Penicidin, Terinin, NSC8120
    Molecular Weight:
    154.12
    Molecular Formula:
    C7H6O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $44.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Purvalanol A | CDK inhibitor

    CAS:
    212844-53-6
    Catalog Number:
    10-2868
    Activity:
    CDK Inhibitor
    Chemical Name:
    (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol
    Alternate Names:
    NG-60
    Molecular Weight:
    388.89
    Molecular Formula:
    C19H25ClN6O
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    Pale green solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Salubrinal | eIF2α Phosphatase inhibitor

    CAS:
    405060-95-9
    Catalog Number:
    10-4517
    Activity:
    eIF2α Phosphatase inhibitor
    Chemical Name:
    3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide
    Molecular Weight:
    479.81
    Molecular Formula:
    C21H17Cl3N4OS
    Solubility:
    Soluble in DMSO (up to 25 mg/ml),
    Physical Properties:
    Beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • STF-083010 | IRE1 inhibitor

    CAS:
    307543-71-1
    Catalog Number:
    10-1510
    Activity:
    Inhibits IRE1
    Chemical Name:
    N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide
    Molecular Weight:
    317.39
    Molecular Formula:
    C15H11NO3S2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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