Programmed cell death

  • Mitomycin C | DNA crosslinking and damaging agent

    CAS:
    50-07-7
    Catalog Number:
    10-1170
    Activity:
    DNA crosslinking and damaging agent
    Chemical Name:
    Natural fermentation product from Streptomyces sp.
    Molecular Weight:
    334.33
    Molecular Formula:
    C15H18N4O5
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).
    Physical Properties:
    Blue-violet solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.
    Shipping Code:
    RT
    From $55.00
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  • Necrostatin-1 | Inhibits necroptosis

    CAS:
    4311-88-0
    Catalog Number:
    10-1162
    Activity:
    Inhibits necroptosis
    Chemical Name:
    5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-Imidazolidinone
    Molecular Weight:
    259.33
    Molecular Formula:
    C13H13N3OS
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied.  Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $55.00
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  • Necrostatin-34 | RIP1 kinase inhibitor

    CAS:
    375835-43-1
    Catalog Number:
    10-4684
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  • Necrosulfonamide | Necroptosis inhibitor / MLKL inhibitor

    CAS:
    1360614-48-7
    Catalog Number:
    10-4860
    Activity:
    Necroptosis inhibitor / MLKL inhibitor
    Chemical Name:
    (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide
    Molecular Weight:
    461.47
    Molecular Formula:
    C18H15N5O6S2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • Nigericin Na | Induces rapid intracellular acidification

    CAS:
    28643-80-3
    Catalog Number:
    10-2089
    Activity:
    Induces rapid intracellular acidification
    Alternate Names:
    Antibiotic K178, Antibiotic X-464, Azalomycin M, PolyetherinA
    Molecular Weight:
    746.96
    Molecular Formula:
    C40H57O11 Na
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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