Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Dexamethasone | Apoptosis inducing glucocorticoid

    CAS:
    50-02-2
    Catalog Number:
    10-1134
    Activity:
    Apoptosis inducing glucocorticoid
    Chemical Name:
    (11α,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
    Molecular Weight:
    392.46
    Molecular Formula:
    C22H29FO5
    Solubility:
    Soluble in DMSO (up to 40 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
    Shipping Code:
    RT
    From $60.00
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  • Dexrazoxane | Iron chelator/Ferroptosis inhibitor

    CAS:
    24584-09-6
    Catalog Number:
    10-2606
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  • Diazoxide | K-ATP channel activator

    CAS:
    364-98-7
    Catalog Number:
    10-2237
    Activity:
    K-ATP channel activator
    Chemical Name:
    7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
    Molecular Weight:
    230.67
    Molecular Formula:
    C8H7ClN2O2S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Dihydroergotamine mesylate | Vascular serotonin receptor agonist

    CAS:
    6190-39-2
    Catalog Number:
    10-3400
    Activity:
    Vascular serotonin receptor agonist
    Chemical Names:
    (5’a,10a)-9,10-Dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)ergotaman-3′,6′,18-trione, mesylate
    Molecular Weight:
    679.79
    Molecular Formula:
    C33H37N5O5·CH3SO3H
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $30.00
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  • Diltiazem | Calcium channel blocker

    CAS:
    33286-22-5
    Catalog Number:
    10-1139
    Activity:
    Calcium channel blocker
    Chemical Name:
    (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(methoxyphenyl)-1,5-benzothiazepin-4-(5H)-one hydrochloride
    Molecular Weight:
    450.98
    Molecular Formula:
    C22H26N2O4S • HCl
    Solubility:
    Soluble in DMSO (up to 45 mg/ml) or in Water (up to 50 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Dipyridamole | Pan-specific PDE inhibitor

    CAS:
    58-32-2
    Catalog Number:
    10-1095
    Activity:
    Pan-specific PDE inhibitor
    Chemical Name:
    2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
    Alternate Names:
    NSC-515776
    Molecular Weight:
    504.63
    Molecular Formula:
    C24H40N8O4
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
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