Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Dihydroergotamine mesylate | Vascular serotonin receptor agonist
From $30.00CAS:6190-39-2Catalog Number:10-3400Activity:Vascular serotonin receptor agonistChemical Names:(5’a,10a)-9,10-Dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)ergotaman-3′,6′,18-trione, mesylateMolecular Weight:679.79Molecular Formula:C33H37N5O5·CH3SO3HSolubility:Soluble in DMSO (25 mg/ml)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Diltiazem | Calcium channel blocker
From $50.00CAS:33286-22-5Catalog Number:10-1139Activity:Calcium channel blockerChemical Name:(2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(methoxyphenyl)-1,5-benzothiazepin-4-(5H)-one hydrochlorideMolecular Weight:450.98Molecular Formula:C22H26N2O4S • HClSolubility:Soluble in DMSO (up to 45 mg/ml) or in Water (up to 50 mg/ml)Physical Properties:White or off-white solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dipyridamole | Pan-specific PDE inhibitor
$30.00CAS:58-32-2Catalog Number:10-1095Activity:Pan-specific PDE inhibitorChemical Name:2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidineAlternate Names:NSC-515776Molecular Weight:504.63Molecular Formula:C24H40N8O4Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 5 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Disopyramide | Antiarrhythmic
From $35.00CAS:3737-09-5Catalog Number:10-4302Activity:AntiarrhythmicChemical Name:4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramideMolecular Weight:339.48Molecular Formula:C21H29N3OSolubility:Soluble in DMSO (25 mg/ml) and Ethanol (>35 mg/mL)Physical Properties:White solidPurity:>98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Docetaxel | Microtubule stabilizing agent
From $38.00CAS:114977-28-5Catalog Number:10-2286Activity:Microtubule stabilizing agentAlternate Names:Taxotere, RP-56976, NSC-628503Molecular Weight:807.9Molecular Formula:C43H53NO14Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:98%Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Dofetilide | hERG channel blocker
From $65.00CAS:115256-11-6Catalog Number:10-1151Activity:hERG channel blockerAlternate Names:TikosynChemical Name:N-[4-(2-{[2-(4-Methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamideMolecular Weight:441.56Molecular Formula:C19H27N3O5S2Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
