Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Erlotinib HCl | EGFR Kinase inhibitor

    CAS:
    183319-69-9
    Catalog Number:
    10-2135
    Activity:
    EGFR Kinase inhibitor
    Chemical Name:
    N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
    Molecular Weight:
    429.91
    Molecular Formula:
    C22H23N3O4 HCl
    Solubility:
    Soluble in DMSO (up to 18 mg/ml with warming).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $35.00
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  • Ethacrynic acid chemical structure

    Ethacrynic acid | Glutathione transferase inhibitor

    CAS:
    58-54-8
    Catalog Number:
    10-2826
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  • Etoposide | Topoisomerase II inhibitor

    CAS:
    33419-42-0
    Catalog Number:
    10-1123
    Activity:
    Topoisomerase II inhibitor
    Chemical Name:
    4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-ß-D-glucopyranoside
    Molecular Weight:
    588.56
    Molecular Formula:
    C29H32O13
    Solubility:
    Soluble in DMSO (up to 30 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
    Shipping Code:
    RT
    From $50.00
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  • Everolimus | mTOR inhibitor

    CAS:
    159351-69-6
    Catalog Number:
    10-2136
    Activity:
    mTOR inhibitor
    Alternate Names:
    SDZ RAD; RAD001
    Chemical Name:
    40-O-(2-Hydroxyethyl)rapamycin
    Molecular Weight:
    958.25
    Molecular Formula:
    C53H84NO14
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Ezetimibe | Cholesterol absorption inhibitor

    CAS:
    163222-33-1
    Catalog Number:
    10-2027
    Activity:
    Cholesterol absorption inhibitor
    Chemical Name:
    (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidine-2-one
    Alternate Names:
    SCH 58235; Ezetrol
    Molecular Weight:
    409.43
    Molecular Formula:
    C24H21F2NO3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • Fasudil HCl | ROCK inhibitor

    CAS:
    105628-07-7
    Catalog Number:
    10-2137
    Activity:
    ROCK inhibitor
    Alternate Names:
    HA-1077
    Chemical Name:
    1-(5-Isoquinolinesulfonyl)homopiperazine HCl
    Molecular Weight:
    327.84
    Molecular Formula:
    C14H17N3O2S HCl
    Solubility:
    Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $52.00
    View Product This product has multiple variants. The options may be chosen on the product page
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