BiochemicalTargets

Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Fasudil HCl | ROCK inhibitor

    CAS:
    105628-07-7
    Catalog Number:
    10-2137
    Activity:
    ROCK inhibitor
    Alternate Names:
    HA-1077
    Chemical Name:
    1-(5-Isoquinolinesulfonyl)homopiperazine HCl
    Molecular Weight:
    327.84
    Molecular Formula:
    C14H17N3O2S HCl
    Solubility:
    Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $52.00
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  • Felodipine | L-type Ca channel blocker

    CAS:
    72509-76-3
    Catalog Number:
    10-2020
    Activity:
    L-type Ca channel blocker
    Chemical Name:
    3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
    Molecular Weight:
    384.25
    Molecular Formula:
    C18H19Cl2NO4
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • FK-506 | FKBP inhibitor

    CAS:
    104987-11-3
    Catalog Number:
    10-1103
    Activity:
    FKBP inhibitor
    Alternate Names:
    Tacrolimus
    Molecular Weight:
    804.04
    Molecular Formula:
    C44H69NO12
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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  • Flecainide acetate | Sodium channel blocker

    CAS:
    54143-56-5
    Catalog Number:
    10-2992
    Activity:
    Sodium channel blocker
    Chemical Name:
    N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate
    Molecular Weight:
    474.39
    Molecular Formula:
    C17H20F6N3O3 • C2H4O2
    Solubility:
    Soluble in DMSO (up to 45 mg/ml) or in Water (up to 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Fludarabine | DNA biosynthesis inhibitor

    CAS:
    21679-14-1
    Catalog Number:
    10-5047
    Activity:
    DNA synthesis inhibitor
    Chemical Names:
    9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine; F-ara-A; NSC118218
    Molecular Weight:
    285.23
    Molecular Formula:
    C10H12FN5O4
    Solubility:
    Soluble in DMSO (30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Flumazenil | Benzodiazepine antagonist

    CAS:
    78755-81-4
    Catalog Number:
    10-1081
    Activity:
    Benzodiazepine antagonist
    Chemical Name:

    8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester

    Alternate Names:

    Ro 1722;  Ro 15-1788

    Molecular Weight:
    303.29
    Molecular Formula:
    C15H14FN3O3
    Solubility:
    Soluble in DMSO (up to 8 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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