Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Ezetimibe | Cholesterol absorption inhibitor
From $55.00CAS:163222-33-1Catalog Number:10-2027Activity:Cholesterol absorption inhibitorChemical Name:(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidine-2-oneAlternate Names:SCH 58235; EzetrolMolecular Weight:409.43Molecular Formula:C24H21F2NO3Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml)Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Fasudil HCl | ROCK inhibitor
From $52.00CAS:105628-07-7Catalog Number:10-2137Activity:ROCK inhibitorAlternate Names:HA-1077Chemical Name:1-(5-Isoquinolinesulfonyl)homopiperazine HClMolecular Weight:327.84Molecular Formula:C14H17N3O2S HClSolubility:Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
Felodipine | L-type Ca channel blocker
From $50.00CAS:72509-76-3Catalog Number:10-2020Activity:L-type Ca channel blockerChemical Name:3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylateMolecular Weight:384.25Molecular Formula:C18H19Cl2NO4Solubility:Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml).Physical Properties:White solidPurity:>98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
FK-506 | FKBP inhibitor
From $50.00CAS:104987-11-3Catalog Number:10-1103Activity:FKBP inhibitorAlternate Names:TacrolimusMolecular Weight:804.04Molecular Formula:C44H69NO12Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Flecainide acetate | Sodium channel blocker
From $50.00CAS:54143-56-5Catalog Number:10-2992Activity:Sodium channel blockerChemical Name:N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetateMolecular Weight:474.39Molecular Formula:C17H20F6N3O3 • C2H4O2Solubility:Soluble in DMSO (up to 45 mg/ml) or in Water (up to 10 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Fludarabine | DNA biosynthesis inhibitor
From $45.00CAS:21679-14-1Catalog Number:10-5047Activity:DNA synthesis inhibitorChemical Names:9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine; F-ara-A; NSC118218Molecular Weight:285.23Molecular Formula:C10H12FN5O4Solubility:Soluble in DMSO (30 mg/ml)Physical Properties:White solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
