Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Enasidenib | Inhibitor of IDH2
From $45.00CAS:1446502-11-9Catalog Number:10-4660Activity:Inhibitor of IDH2Chemical Name:2-Methyl-1-[[4-[6(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-2-propanolAlternate Names:AG-221Molecular Weight:473.38Molecular Formula:C19H17F6N7OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Eniluracil | Dihydropyrimidine dehydrogenase inhibitor
From $40.00CAS:59989-18-3Catalog Number:10-4600Activity:Dihydropyrimidine dehydrogenase inhibitorChemical Name:5-EthynyluracilAlternate Names:GW776C85Molecular Weight:136.11Molecular Formula:C6H4N2O2Solubility:Soluble in DMSOPhysical Properties:Yellow solidPurity:97% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Entacapone | COMT inhibitor
From $40.00CAS:130929-57-6Catalog Number:10-2025Activity:COMT inhibitor – anti-ParkinsonsChemical Name:(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamideMolecular Weight:305.29Molecular Formula:C14H15N3O5Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 3 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Enzalutamide | Non-steroidal antiandrogen
From $40.00CAS:915087-33-1Catalog Number:10-3910Activity:Non-steroidal antiandrogenChemical Names:4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide; MDV3100Molecular Weight:464.44Molecular Formula:C21H16F4N4O2SSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White to off-white solidPurity:99% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Epirubicin HCl | DNA damaging agent
From $48.00CAS:56390-09-1Catalog Number:10-2761Activity:DNA damaging agentChemical Name:4′-EpidoxorubicinMolecular Weight:579.99Molecular Formula:C27H29NO11 HClSolubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 5 mg/ml).Physical Properties:Red orange solidPurity:97% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
Erlotinib HCl | EGFR Kinase inhibitor
From $35.00CAS:183319-69-9Catalog Number:10-2135Activity:EGFR Kinase inhibitorChemical Name:N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochlorideMolecular Weight:429.91Molecular Formula:C22H23N3O4 HClSolubility:Soluble in DMSO (up to 18 mg/ml with warming).Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
