Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Cyclosporin A | Inhibits mitochondrial permeability pore opening
From $50.00CAS:59865-13-3Catalog Number:10-1119Activity:Inhibits mitochondrial permeability pore openingMolecular Weight:1202.65Molecular Formula:C62H111N11O12Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:99% by TLCStorage Temperature:-20°CStability:Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Cyclothiazide | AMPA receptor positive allosteric modulator
From $50.00CAS:2259-96-3Catalog Number:10-2449Activity:AMPA receptor positiv e allosteric modulatorChemical Name:6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxideAlternate Names:LY-35483Molecular Weight:389.88Molecular Formula:C14H16ClN3O4S2Solubility:Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 9 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Cytarabine | Anticancer agent
From $40.00CAS:147-94-4Catalog Number:10-1268Activity:Anticancer agentChemical Names:4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone; Arabinocytidine; Cytosine β-D-Arabinofuranoside; U-19920A; Ara-CMolecular Weight:243.22Molecular Formula:C9H13N3O5Solubility:Soluble in DMSO (12 mg/ml) or water (24 mg/mL)Physical Properties:White to off-white solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied from date of purchase. Solutions in DMSO or water may be stored at -20°C for up to 1 month.Shipping Code:RT -
D(+)-Cycloserine | NMDA, glycine site partial agonist
From $60.00CAS:68-41-7Catalog Number:10-2279Activity:NMDA, glycine site partial agonistChemical Name:(R)-4-Amino-3-isoxazolidoneMolecular Weight:102.09Molecular Formula:C3H6N2O2Solubility:Soluble in Water (up to 100 mg/ml)Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Dabrafenib | B-Raf mutant inhibitor
From $40.00CAS:1195765-45-7Catalog Number:10-1569Activity:B-Raf mutant inhibitorChemical Name:N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamideAlternate Names:GSK2118436Molecular Weight:519.56Molecular Formula:C23H20F3N5O2SSolubility:Soluble in DMSO (up to 30 mg/ml with warming), or in Ethanol (up to 1 mg/ml with warming).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dantrolene Na | SR calcium release inhibitor
From $50.00CAS:14663-23-1Catalog Number:10-2208Activity:SR calcium release inhibitorChemical Name:1-[(5-(p-Nitrophenyl)furfurylidene)amino]hydantoin sodium saltMolecular Weight:336.23Molecular Formula:C14H9N4O5 NaSolubility:Soluble in DMSO (up to 3 mg/ml) or in a 1:1 mix of DMF and Ethanol (up to 20 mg/ml)Physical Properties:Orange solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF/ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT
