Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Doxycycline monohydrate | Broad spectrum antibiotic
CAS:17086-28-1Catalog Number:10-3765 -
Duvelisib | PI3Kdelta/gamma inhibitor
From $65.00CAS:1201438-56-3Catalog Number:10-4788Activity:PI3Kδ/γ inhibitor/Cancer immunotherapy enhancerChemical Name:8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-oneAlternative Name:IPI-145Molecular Weight:416.87Molecular Formula:C22H17ClN6OSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dyclonine HCl | Mitochondrial function enhancer
From $35.00CAS:536-43-6Catalog Number:10-3895Activity:Mitochondrial function enhancerChemical Names:4′-Butoxy-3-piperidinopropiophenone, hydrochlorideMolecular Weight:325.87Molecular Formula:C18H27NO2·HClSolubility:Soluble in DMSO (20 mg/ml); Water (25 mg/ml)Physical Properties:White solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.Shipping Code:RT -
Enasidenib | Inhibitor of IDH2
From $45.00CAS:1446502-11-9Catalog Number:10-4660Activity:Inhibitor of IDH2Chemical Name:2-Methyl-1-[[4-[6(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-2-propanolAlternate Names:AG-221Molecular Weight:473.38Molecular Formula:C19H17F6N7OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Eniluracil | Dihydropyrimidine dehydrogenase inhibitor
From $40.00CAS:59989-18-3Catalog Number:10-4600Activity:Dihydropyrimidine dehydrogenase inhibitorChemical Name:5-EthynyluracilAlternate Names:GW776C85Molecular Weight:136.11Molecular Formula:C6H4N2O2Solubility:Soluble in DMSOPhysical Properties:Yellow solidPurity:97% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Entacapone | COMT inhibitor
From $40.00CAS:130929-57-6Catalog Number:10-2025Activity:COMT inhibitor – anti-ParkinsonsChemical Name:(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamideMolecular Weight:305.29Molecular Formula:C14H15N3O5Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 3 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT
