Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Docetaxel | Microtubule stabilizing agent
From $40.00CAS:114977-28-5Catalog Number:10-2286Activity:Microtubule stabilizing agentAlternate Names:Taxotere, RP-56976, NSC-628503Molecular Weight:807.9Molecular Formula:C43H53NO14Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:98%Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Dofetilide | hERG channel blocker
From $65.00CAS:115256-11-6Catalog Number:10-1151Activity:hERG channel blockerAlternate Names:TikosynChemical Name:N-[4-(2-{[2-(4-Methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamideMolecular Weight:441.56Molecular Formula:C19H27N3O5S2Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Doxorubicin HCl | DNA damaging agent
From $50.00CAS:25316-40-9Catalog Number:10-2130Activity:DNA damaging agentAlternate Names:Adriamycin; NSC-123127Molecular Weight:579.99Molecular Formula:C27H29NO11 HClSolubility:Soluble in Water (up to 25 mg/ml).Physical Properties:Red-orange solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
Duvelisib | PI3Kdelta/gamma inhibitor
From $65.00CAS:1201438-56-3Catalog Number:10-4788Activity:PI3Kδ/γ inhibitor/Cancer immunotherapy enhancerChemical Name:8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-oneAlternative Name:IPI-145Molecular Weight:416.87Molecular Formula:C22H17ClN6OSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dyclonine HCl | Mitochondrial function enhancer
From $35.00CAS:536-43-6Catalog Number:10-3895Activity:Mitochondrial function enhancerChemical Names:4′-Butoxy-3-piperidinopropiophenone, hydrochlorideMolecular Weight:325.87Molecular Formula:C18H27NO2·HClSolubility:Soluble in DMSO (20 mg/ml); Water (25 mg/ml)Physical Properties:White solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.Shipping Code:RT
