Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Dabrafenib | B-Raf mutant inhibitor
From $40.00CAS:1195765-45-7Catalog Number:10-1569Activity:B-Raf mutant inhibitorChemical Name:N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamideAlternate Names:GSK2118436Molecular Weight:519.56Molecular Formula:C23H20F3N5O2SSolubility:Soluble in DMSO (up to 30 mg/ml with warming), or in Ethanol (up to 1 mg/ml with warming).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dantrolene Na | SR calcium release inhibitor
From $50.00CAS:14663-23-1Catalog Number:10-2208Activity:SR calcium release inhibitorChemical Name:1-[(5-(p-Nitrophenyl)furfurylidene)amino]hydantoin sodium saltMolecular Weight:336.23Molecular Formula:C14H9N4O5 NaSolubility:Soluble in DMSO (up to 3 mg/ml) or in a 1:1 mix of DMF and Ethanol (up to 20 mg/ml)Physical Properties:Orange solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF/ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Daptomycin | Antibiotic
From $50.00CAS:103060-53-3Catalog Number:10-2692Activity:AntibioticAlternate Names:Cubicin; LY146032Molecular Weight:1620.71Molecular Formula:C72H101N17O26Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 50 mg/ml).Physical Properties:Pale yellow solidPurity:95% by HPLCStorage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Darunavir | HIV-1 protease inhibitor
From $60.00CAS:206361-99-1Catalog Number:10-4930Activity:HIV-1 protease inhibitorChemical Names:[(3aS,4R,6aR)-2,3,3a,5,6a-Hexahydrofuro[2,3-b]furan-4-yl] N-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate; UIC-94017; TMC114Molecular Weight:547.67Molecular Formula:C27H37N3O7SSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dasatinib | Src and Bcr/Abl inhibitor
From $50.00CAS:302962-49-8Catalog Number:10-2126Activity:Src and Bcr/Abl inhibitorAlternate Names:BMS-354825Chemical Name:N-(2-Chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino) thiazole-5-carboxamideMolecular Weight:488.01Molecular Formula:C22H26ClN7O2SSolubility:Soluble in DMSO (up to 200 mg/ml).Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.Shipping Code:RT -
Daunorubicin HCl | DNA Damaging Agent / Anticancer Agent
From $60.00CAS:23541-50-6Catalog Number:10-2429Activity:DNA Damaging Agent / Anticancer agentAlternate Names:Daunomycin; rubidomycin; RP-13057Molecular Weight:536.98Molecular Formula:C27H39NO10 • HClSolubility:Soluble in water (up to 25 mg/ml)Physical Properties:Red solidPurity:95% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT
