BiochemicalTargets

Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Telaprevir | Hepatitis C protease inhibitor

    CAS:
    402957-28-2
    Catalog Number:
    10-4929
    Activity:
    HCV protease inhibitor
    Chemical Names:
    (3S,3aS,6aR)-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
    Alternate Name:
    VX-950
    Molecular Weight:
    679.86
    Molecular Formula:
    C36H53N7O6
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Temozolomide | Autophagy inducer

    CAS:
    85622-93-1
    Catalog Number:
    10-2390
    Activity:
    Autophagy inducer
    Alternate Names:
    NSC-362856
    Chemical Name:
    8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one
    Molecular Weight:
    194.15
    Molecular Formula:
    C6H6N6O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • Tepotinib | Selective c-MET inhibitor

    CAS:
    1100598-32-0
    Catalog Number:
    10-5322
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  • Teprenone | HSP70 inducer

    CAS:
    6809-52-5
    Catalog Number:
    10-2262
    Activity:
    HSP70 inducer
    Alternate Names:
    Geranylgeranylacetone; GGA
    Chemical Name:
    6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
    Molecular Weight:
    350.55
    Molecular Formula:
    C23H38O
    Solubility:
    Soluble in DMSO (up to 30 mg/ml).
    Physical Properties:
    Colorless oil
    Purity:
    >95% by GC
    NMR (Confirms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Terazocin HCl | Adrenergic antagonist

    CAS:
    63074-08-8
    Catalog Number:
    10-2379
    Activity:
    Adrenergic antagonist
    Chemical Name:
    1-(4-Amino-6,7-dimethoxy-2-quinazolinyl-4-[(tetrahydro-2-furanyl)carbonyl]piperazine
    Molecular Weight:
    423.88
    Molecular Formula:
    C19H25N5O4
    Solubility:
    Soluble in Water (up to 20 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Terguride | Dopamine D2 agonist

    CAS:
    37686-84-3
    Catalog Number:
    10-2308
    Activity:
    Dopamine D2 agonist
    Alternate Names:
    S(+)-Terguride
    Chemical Name:
    S(+)-N,N-Diethyl-N'([8α]-6-methylergolin-8-yl)urea
    Molecular Weight:
    340.47
    Molecular Formula:
    C20H28N4O
    Solubility:
    Soluble in DMSO or in Ethanol.
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $125.00
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