Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Sorafenib | Multi-kinase inhibitor
From $40.00CAS:475207-59-1Catalog Number:10-2174Activity:Inhibitor of Raf-1 and other kinasesAlternate Names:BAY 43-9006Chemical Name:4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamideMolecular Weight:464.83Molecular Formula:C21H16ClF3N4O3Solubility:Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 3 mg/ml).Physical Properties:Off-white solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
Stavudine | HIV reverse transcriptase inhibitor
From $52.00CAS:3056-17-5Catalog Number:10-1266Activity:HIV reverse transcriptase inhibitorChemical Names:2’,3’-Didehydro-3’-deoxythymidineAlternate Name:BMY 27857; d4TMolecular Weight:224.22Molecular Formula:C10H12N2O4Solubility:Soluble in DMSO (20 mg/ml); water (20 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Sulconazole | Antifungal/ Prevents cancer stem cell formation
From $55.00CAS:61318-91-0Catalog Number:10-3955Activity:Antifungal/Prevents cancer stem cell formationChemical Names:1-[2-[(4-Chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole nitrateMolecular Weight:460.75Molecular Formula:C18H15Cl3N2S·HNO3Solubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Sulfasalazine | Anti-inflammatory / antibiotic
From $20.00CAS:599-79-1Catalog Number:10-4566Activity:Anti-inflammatory / antibioticChemical Name:2-Hydroxy-5-{{4-[(2-pyridinylamino)sulfonyl]phenyl}azo}benzoic acidMolecular Weight:398.39Molecular Formula:C18H14N4O5SSolubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Orange solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
Sunitinib malate | VEGFR, PDGFR kinase inhibitor
From $60.00CAS:341031-54-7Catalog Number:10-1078Activity:VEGFR, PDGFR kinase inhibitorAlternate Names:SU-11248Chemical Name:N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide malateMolecular Weight:532.57Molecular Formula:C22H27FN4O4 C4H6O5Solubility:Soluble in DMSO (up to 13 mg/ml).Physical Properties:Orange solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Suplatast tosilate | Immunomodulator
From $55.00CAS:94055-76-2Catalog Number:10-2896Activity:ImmunomodulatorChemical Name:[3-[[4-(3-Ethoxy-2-hydroxypropoxy)phenyl]amino]-3-oxopropyl]dimethylsulfonium 4-MethylbenzenesulfonateAlternate Names:IPD 1151TMolecular Weight:499.64Molecular Formula:C16H26NO4S • C7H7O3SSolubility:Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT
