BiochemicalTargets

Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Tafamidis | Transthyretin stabilizer

    CAS:
    594839-88-0
    Catalog Number:
    10-3743
    Activity:
    Transthyretin stabilizer
    Chemical Name:
    2-(3,5-Dichlorophenyl)-6-benzoxazolecarboxylic acid
    Alternate Name:
    PF-06291826
    Molecular Weight:
    308.12
    Molecular Formula:
    C14H7Cl2NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • Tamoxifen citrate | ER Antagonist/GPR30 agonist

    CAS:
    54965-24-1
    Catalog Number:
    10-1256
    Activity:
    ER Antagonist/GPR30 agonist
    Alternate Names:
    ICI-46474
    Chemical Name:
    (2)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine citrate
    Molecular Weight:
    563.65
    Molecular Formula:
    C26H29NO·C6H8O7
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $30.00
  • Taxol | Microtubule stabilizing agent

    CAS:
    33069-62-4
    Catalog Number:
    10-2095
    Activity:
    Microtubule stabilizing agent
    Alternate Names:
    Paclitaxel
    Molecular Weight:
    853.91
    Molecular Formula:
    C47H51NO14
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00
  • Telaprevir | Hepatitis C protease inhibitor

    CAS:
    402957-28-2
    Catalog Number:
    10-4929
    Activity:
    HCV protease inhibitor
    Chemical Names:
    (3S,3aS,6aR)-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
    Alternate Name:
    VX-950
    Molecular Weight:
    679.86
    Molecular Formula:
    C36H53N7O6
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • Temozolomide | Autophagy inducer

    CAS:
    85622-93-1
    Catalog Number:
    10-2390
    Activity:
    Autophagy inducer
    Alternate Names:
    NSC-362856
    Chemical Name:
    8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one
    Molecular Weight:
    194.15
    Molecular Formula:
    C6H6N6O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
  • Teprenone | HSP70 inducer

    CAS:
    6809-52-5
    Catalog Number:
    10-2262
    Activity:
    HSP70 inducer
    Alternate Names:
    Geranylgeranylacetone; GGA
    Chemical Name:
    6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
    Molecular Weight:
    350.55
    Molecular Formula:
    C23H38O
    Solubility:
    Soluble in DMSO (up to 30 mg/ml).
    Physical Properties:
    Colorless oil
    Purity:
    >95% by GC
    NMR (Confirms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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