Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Rosiglitazone maleate | PPAR gamma agonist
From $55.00CAS:155141-29-0Catalog Number:10-1012Activity:PPARγ agonistAlternate Names:Avandia; BRL49653Chemical Name:5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione maleateMolecular Weight:357.43Molecular Formula:C18H19N3O3SSolubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 monthsShipping Code:RT -
Rucaparib phosphate | PARP1 inhibitor
From $70.00CAS:459868-92-9Catalog Number:10-3321Activity:PARP1 inhibitorChemical Name:8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-oneAlternate Name:AG-14699; PF01367338Molecular Weight:421.36Molecular Formula:C19H18FN3O • H3PO4Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Rufinamide | Anticonvulsant / Improves cognition
From $25.00CAS:106308-44-5Catalog Number:10-4275Activity:Anticonvulsant / Improves cognitionChemical Name:1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamideMolecular Weight:238.19Molecular Formula:C10H8F2N4O2Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Ruxolitinib | JAK inhibitor
From $65.00CAS:941678-49-5Catalog Number:10-4511Activity:JAK inhibitorAlternate Names:INCB 018424Chemical Name:βR-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrileMolecular Weight:306.37Molecular Formula:C17H18N6Solubility:Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Safinamide | MAO-B inhibitor; Parkinson’s therapeutic
From $48.00CAS:133865-89-1Catalog Number:10-2924Activity:MAO-B inhibitor; Parkinson’s therapeuticChemical Name:(S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamideAlternate Name:FCE-26743; PNU-151774E; NW-1015Molecular Weight:302.34Molecular Formula:C17H19FN2O2Solubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
SAHA | HDAC inhibitor
From $35.00CAS:149647-78-9Catalog Number:10-1067Activity:HDAC inhibitorAlternate Names:VorinostatChemical Name:Suberoylanilide-hydroxamic acidMolecular Weight:264.33Molecular Formula:C14H20N2O3Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.Shipping Code:RT
