Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Bleomycin sulfate | Induces double strand DNA breaks
From $75.00CAS:9041-93-4Catalog Number:10-2623Activity:Fibrosis-inducing agentSource:From Streptomyces verticillusMolecular Weight:1512.62Molecular Formula:C55H85N17O25S4Solubility:Soluble in Water (up to 20 mg/ml)Physical Properties:White or off-white solidPurity:Contains a mixture of A2 (~70%) and B2 (~30%) forms
95% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from the date of purchase. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Boceprevir | Antiviral, SARS-CoV2 Mpro inhibitor
From $70.00CAS:394730-60-0Catalog Number:10-5087Activity:Anitviral, SARS-CoV-2 Mpro inhibitorMolecular Weight:519.68Molecular Formula:C27H45N5O5Solubility:Soluble in DMSO (up to 15 mg/ml with warming)Physical Properties:White or off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Bosutinib | Dual Src/Abl kinase inhibitor
From $40.00CAS:380843-75-4Catalog Number:10-2122Activity:Dual Src/Abl kinase inhibitorChemical Names:4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrileAlternate Name:SKI-606Molecular Weight:530.45Molecular Formula:C26H29Cl2N5O3Solubility:Soluble in DMSO (100 mg/ml); Ethanol (up to 25 mg/ml with warming)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Brigatinib | pan-ALK inhibitor
From $50.00CAS:1197953-54-0Catalog Number:10-5034Activity:pan-ALK inhibitorChemical Names:5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4- pyrimidinediamineAlternate Name:AP26113Molecular Weight:584.02Molecular Formula:C29H39ClN7O2PSolubility:Soluble in DMSO (1 mg/ml with warming)Physical Properties:White to off-white solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Bupropion HCl | Monoamine transporter inhibitor
From $60.00CAS:31677-93-7Catalog Number:10-2462Activity:Monoamine transporter inhibitorChemical Names:1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochlorideMolecular Weight:276.20Molecular Formula:C13H18ClNO·HClSolubility:Soluble in DMSO (40 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Cabozantinib | Met and VEGFR2 inhibitor
From $50.00CAS:849217-68-1Catalog Number:10-3231Activity:Met and VEGFR2 inhibitorChemical Name:N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideAlternate Names:XL-184; BMS-907351; CarbozantinibMolecular Weight:501.51Molecular Formula:C28H24FN3O5Solubility:Soluble in DMSOPhysical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
